Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | AR | P10275 | 1/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
| ▸ | PIM1 | P11309 | 1/20 | 0.31 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.31 |
| ▸ | PTGIR | P43119 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.30 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15630205 | 0.90 | ADRA2A (0.32) | MEN1KMT2ASMN1; SMN2OPRK1PIM1 | |
| SCHEMBL15619279 | 0.89 | MEN1 (0.32) | MEN1KMT2ASMN1; SMN2CNR1PTGIR | |
| SCHEMBL15630218 | 0.86 | MEN1 (0.33) | MEN1KMT2ASMN1; SMN2CNR1POLB | |
| SCHEMBL535211 | 0.81 | TDP1 (0.32) | SMN1; SMN2TDP1 | |
| SCHEMBL14869176 | 0.80 | LMNA (0.30) | — | |
| SCHEMBL158453 | 0.77 | AAK1 (0.32) | MEN1KMT2A | |
| SCHEMBL3106096 | 0.76 | AAK1 (0.33) | — | |
| SCHEMBL15630270 | 0.76 | POLB (0.34) | MEN1KMT2ASMN1; SMN2POLBCTDSP1 | |
| SCHEMBL3110409 | 0.76 | HTT (0.33) | SMN1; SMN2POLB | |
| SCHEMBL2869073 | 0.76 | AAK1 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014044642-A1 | N-CYCLOPROPYLMETHYL-2-(QUINOLIN-6-YLOXY)-ACETAMIDE DERIVATIVES AND THEIR USE AS FUNGICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2014-03-27 | — | — | WO | disclosed |