SCHEMBL15633355

SCHEMBL15633355

CN(C)c1ccccc1C(O)=S

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.59
GAA P10253 4/20 0.59
TSHR P16473 3/20 0.59
ALDH1A1 P00352 2/20 0.59
SMN1; SMN2 Q16637 2/20 0.59
TP53 P04637 1/20 0.59
CNR2 P34972 2/20 0.41
HSP90AA1 P07900 1/20 0.40
HTR6 P50406 1/20 0.38
KDM4E B2RXH2 1/20 0.38
MASP2 O00187 1/20 0.38
MGLL Q99685 2/20 0.38
FAAH O00519 1/20 0.38
PHGDH O43175 1/20 0.38
CA12 O43570 1/20 0.38
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
CA9 Q16790 1/20 0.38
CHEK1 O14757 1/20 0.38
NEK2 P51955 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5828459 0.81 ALDH1A1 (0.53) MAPTGAATSHRALDH1A1SMN1; SMN2
SCHEMBL4352832 0.80 MAPT (0.57) MAPTGAATSHRALDH1A1SMN1; SMN2
SCHEMBL15632929 0.80 MAPT (0.57) MAPTGAATSHRALDH1A1SMN1; SMN2
SCHEMBL1583381 0.79 MAPT (0.38) MAPTGAATSHRALDH1A1SMN1; SMN2
SCHEMBL2491643 0.78 MAPT (0.67) MAPTGAATSHRALDH1A1SMN1; SMN2
SCHEMBL11874450 0.78 ALDH1A1 (0.50) MAPTGAATSHRALDH1A1SMN1; SMN2
SCHEMBL7667696 0.77 ALDH1A1 (0.59) MAPTGAATSHRALDH1A1SMN1; SMN2
SCHEMBL15240 0.77 ALDH1A1 (0.72) MAPTGAATSHRALDH1A1SMN1; SMN2
SCHEMBL1582993 0.77 ALDH1A1 (0.35) MAPTGAATSHRALDH1A1SMN1; SMN2
Phthalic Acid SCHEMBL25407447 0.76 ALDH1A1 (0.69) MAPTGAATSHRALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9457234-B2 Golf ball DUNLOP SPORTS CO. LTD. (JP) 2016-10-04 US disclosed
US-9302158-B2 Golf ball DUNLOP SPORTS CO., LTD. (JP) 2016-04-05 US disclosed
US-20140357406-A1 GOLF BALL DUNLOP SPORTS CO., LTD. (JP) 2014-12-04 US disclosed
US-20140100058-A1 GOLF BALL Dunlop Sprorts Co., Ltd. (JP) 2014-04-10 US disclosed