Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | GAA | P10253 | 4/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.41 |
| ▸ | NEK2 | P51955 | 1/20 | 0.41 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.41 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | EP300 | Q09472 | 1/20 | 0.35 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.35 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15633355 | 0.80 | MAPT (0.59) | MAPTALDH1A1GAASMN1; SMN2TSHR | |
| SCHEMBL147847 | 0.78 | ALDH1A1 (0.69) | MAPTALDH1A1GAASMN1; SMN2TSHR | |
| SCHEMBL15632929 | 0.78 | MAPT (0.57) | MAPTALDH1A1GAASMN1; SMN2TSHR | |
| SCHEMBL2491643 | 0.77 | MAPT (0.67) | MAPTALDH1A1GAASMN1; SMN2TSHR | |
| SCHEMBL4308507 | 0.76 | CHEK1 (0.53) | MAPTALDH1A1GAASMN1; SMN2TSHR | |
| SCHEMBL609919 | 0.75 | ALDH1A1 (0.42) | MAPTALDH1A1GAATSHRTP53 | |
| SCHEMBL5828459 | 0.75 | ALDH1A1 (0.53) | MAPTALDH1A1GAASMN1; SMN2TSHR | |
| SCHEMBL1227388 | 0.73 | MAPT (1.00) | MAPTALDH1A1GAASMN1; SMN2TSHR | |
| SCHEMBL29365484 | 0.73 | MAPT (0.61) | MAPTALDH1A1GAASMN1; SMN2TSHR | |
| SCHEMBL12506468 | 0.73 | MAPT (0.75) | MAPTALDH1A1GAASMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104334629-B | Rubber composition for tire tread and pneumatic tire | 住友橡胶工业株式会社 | 2016-08-24 | — | — | CN | disclosed |
| CN-104334629-A | Tread rubber composition and pneumatic tire | SUMITOMO RUBBER IND | 2015-02-04 | — | — | CN | disclosed |
| WO-2009120826-A1 | 2-ARYL- AND 2-HETEROARYLTHIAZOLYL COMPOUNDS, METHODS FOR THEIR PREPARATION AND USE THEREOF | WYETH (US) | 2009-10-01 | — | — | WO | disclosed |