SCHEMBL1563372

SCHEMBL1563372

CC(CC(C)C)=NNC(=O)c1ccc2ccccc2c1

nearest known ligand 0.58

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.58
ALDH1A1 P00352 1/20 0.58
RAB9A P51151 6/20 0.55
NPC1 O15118 4/20 0.55
KMT2A Q03164 4/20 0.55
MEN1 O00255 3/20 0.55
GAA P10253 2/20 0.55
NSD2 O96028 1/20 0.55
POLB P06746 1/20 0.55
GFER P55789 1/20 0.55
SMN1; SMN2 Q16637 2/20 0.50
KDM4E B2RXH2 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
MAOA P21397 1/20 0.47
MAOB P27338 1/20 0.47
HDAC3 O15379 1/20 0.47
HDAC1 Q13547 1/20 0.47
HDAC2 Q92769 1/20 0.47
PKM P14618 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6635696 1.00 MAPT (0.58) MAPTALDH1A1RAB9ANPC1KMT2A
SCHEMBL1563371 1.00 MAPT (0.58) MAPTALDH1A1RAB9ANPC1KMT2A
SCHEMBL6055335 0.88 PKM (0.60) MAPTALDH1A1RAB9ANPC1KMT2A
SCHEMBL1563270 0.85 MAPT (0.61) MAPTALDH1A1RAB9ANPC1KMT2A
SCHEMBL29586571 0.85 MAPT (0.61) MAPTALDH1A1RAB9ANPC1KMT2A
SCHEMBL1563268 0.85 MAPT (0.61) MAPTALDH1A1RAB9ANPC1KMT2A
SCHEMBL6634931 0.85 MAPT (0.61) MAPTALDH1A1RAB9ANPC1KMT2A
SCHEMBL6635616 0.84 RAB9A (0.55) MAPTALDH1A1RAB9ANPC1KMT2A
SCHEMBL22441541 0.84 RAB9A (0.55) MAPTALDH1A1RAB9ANPC1KMT2A
SCHEMBL6637074 0.83 SMN1; SMN2 (0.65) MAPTALDH1A1RAB9ANPC1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1083199-B1 RUBBER COMPOSITION AND PNEUMATIC TIRE BRIDGESTONE CORP (JP) 2006-08-02 EP claimed
US-6506849-B1 Natural or synthetic rubber; maleimide compound; and polyaniline, hydrazide and/or amine compound; workability, elasticity BRIDGESTONE CORPORATION (JP) 2003-01-14 US claimed
EP-1083199-A1 RUBBER COMPOSITION AND PNEUMATIC TIRE BRIDGESTONE CORPORATION (JP) 2001-03-14 EP claimed
US-9556351-B2 Rubber composition suitable for use as a cap ply in a tire Bridgestone Americas Tire Operations, Inc. (US) 2017-01-31 US disclosed
US-20160040024-A1 RUBBER COMPOSITION SUITABLE FOR USE AS A CAP PLY IN A TIRE BRIDGESTONE AMERICAS TIRE OPERATIONS, LLC 2016-02-11 US disclosed
US-9163127-B2 Rubber composition suitable for use as a cap ply in a tire BRIDGESTONE AMERICAS TIRE OPERATIONS, LLC (US) 2015-10-20 US disclosed
US-20140005320-A1 RUBBER COMPOSITION SUITABLE FOR USE AS A CAP PLY IN A TIRE BRIDGESTONE AMERICAS TIRE OPERATIONS, LLC (US) 2014-01-02 US disclosed
EP-2665771-A2 A RUBBER COMPOSITION SUITABLE FOR USE AS A CAP PLY IN A TIRE Bridgestone Americas Tire Operations, LLC (US) 2013-11-27 EP disclosed
WO-2012099955-A2 A RUBBER COMPOSITION SUITABLE FOR USE AS A CAP PLY IN A TIRE BRIDGESTONE AMERICAS TIRE OPERATIONS, LLC (US) 2012-07-26 WO disclosed
EP-1475408-B1 RUBBER COMPOSITION AND PNEUMATIC TIRE MADE THEREFROM BRIDGESTONE CORP (JP) 2011-04-06 EP disclosed
EP-1083199-B1 RUBBER COMPOSITION AND PNEUMATIC TIRE BRIDGESTONE CORP (JP) 2006-08-02 EP disclosed
US-6787595-B1 WEAR RESISTANCE; LOW HEAT BUILDUP; INCORPORATES CARBON BLACK OF SPECIFIC PROPERTIES BRIDGESTONE CORPORATION (JP) 2004-09-07 US disclosed
EP-1420044-A2 Rubber composition and pneumatic tire Bridgestone Corporation (JP) 2004-05-19 EP disclosed
US-6506849-B1 Natural or synthetic rubber; maleimide compound; and polyaniline, hydrazide and/or amine compound; workability, elasticity BRIDGESTONE CORPORATION (JP) 2003-01-14 US disclosed
US-6380288-B1 LOW HEAT GENERATION PROPERTY, AGING REISTANCE, ALSO FOR PRODUCING VIBRATION ISOLATORS, BELTS AND HOSES AS WELL AS TIRE MATERIALS SUCH AS TIRE TREADS, UNDERTREADS, CARCASSES, SIDE WALLS AND BEADS BRIDGESTONE CORPORATION 2002-04-30 US disclosed
US-20020049294-A1 Rubber composition and heavy duty pneumatic tire using the rubber composition BRIDGESTONE CORPORATION 2002-04-25 US disclosed
EP-1184412-A1 Rubber composition and heavy duty pneumetic tire using the rubber composition Bridgestone Corporation (JP) 2002-03-06 EP disclosed
EP-1095972-A1 Rubber composition and tire Bridgestone Corporation (JP) 2001-05-02 EP disclosed
EP-1083199-A1 RUBBER COMPOSITION AND PNEUMATIC TIRE BRIDGESTONE CORPORATION (JP) 2001-03-14 EP disclosed
EP-0909788-A1 RUBBER COMPOSITION AND PNEUMATIC TIRES Bridgestone Corporation (JP) 1999-04-21 EP disclosed