Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | GLA | P06280 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | FLT1 | P17948 | 1/20 | 0.46 |
| ▸ | FLT4 | P35916 | 1/20 | 0.46 |
| ▸ | KDR | P35968 | 1/20 | 0.46 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.44 |
| ▸ | MYC | P01106 | 1/20 | 0.44 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.44 |
| ▸ | GPR27 | Q9NS67 | 1/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2349044 | 0.98 | DGAT1 (0.66) | DGAT1KDM4EGLANPC1ALDH1A1 | |
| Bromide SCHEMBL25212853 | 0.86 | DGAT1 (0.53) | DGAT1KDM4EGLANPC1ALDH1A1 | |
| SCHEMBL6222444 | 0.86 | RARB (0.56) | DGAT1KDM4EGLALMNARXFP1 | |
| SCHEMBL4464312 | 0.84 | DGAT1 (0.70) | DGAT1KDM4EGLANPC1ALDH1A1 | |
| SCHEMBL25379561 | 0.83 | DGAT1 (0.50) | DGAT1KDM4EGLANPC1ALDH1A1 | |
| SCHEMBL6818016 | 0.83 | DGAT1 (0.63) | DGAT1KDM4EGLANPC1ALDH1A1 | |
| SCHEMBL2554 | 0.83 | KDM4E (0.59) | DGAT1KDM4EGLANPC1ALDH1A1 | |
| SCHEMBL30722862 | 0.83 | KDM4E (0.59) | DGAT1KDM4EGLANPC1ALDH1A1 | |
| SCHEMBL2095201 | 0.81 | DGAT1 (0.66) | DGAT1KDM4EGLANPC1ALDH1A1 | |
| SCHEMBL321094 | 0.81 | DGAT1 (0.66) | DGAT1KDM4EGLANPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2173 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118955313-B | Synthesis method of enzalutamide key intermediate | 安徽峆一药业股份有限公司 | 2025-06-17 | — | — | CN | claimed |
| CN-117820218-B | Preparation method of apatamide and intermediate | 江苏希迪制药有限公司 | 2025-05-27 | — | — | CN | claimed |
| CN-118955313-A | Synthesis method of enzalutamide key intermediate | 安徽峆一药业股份有限公司 | 2024-11-15 | — | — | CN | claimed |
| CN-117820306-A | Axial chiral luminescent material with double luminescent centers and preparation method and application thereof | 南通大学 | 2024-04-05 | — | — | CN | claimed |
| CN-117820218-A | Preparation method of apatamide and intermediate | 江苏希迪制药有限公司 | 2024-04-05 | — | — | CN | claimed |
| CN-117534652-A | Preparation method of apatamide | 黄冈人福药业有限责任公司 | 2024-02-09 | — | — | CN | claimed |
| CN-116903646-A | Axial chiral boron-nitrogen luminescent material and preparation method and application thereof | 南通大学 | 2023-10-20 | — | — | CN | claimed |
| CN-115215791-B | Solvent-free preparation method of organic eutectic material | 北京仿生界面科学未来技术研究院 | 2023-10-03 | — | — | CN | claimed |
| US-20230159524-A1 | METHODS FOR SYNTHESIZING N-(PHENYLSULFONYL)BENZAMIDE COMPOUNDS AND INTERMEDIATES THEREOF | ASCENTAGE PHARMA (SUZHOU) CO., LTD. (CN) | 2023-05-25 | — | — | US | claimed |
| CN-113698310-B | Preparation method of enzalutamide diester intermediate | 江西金丰药业有限公司 | 2023-03-17 | — | — | CN | claimed |
| CN-105753802-B | 3- isopropyl -6- bromine benzoisoxazoles and preparation method thereof | 广东环境保护工程职业学院 | 2018-06-05 | — | — | CN | claimed |
| US-20170190670-A1 | IMPROVED PROCESS FOR THE PREPARATION OF ENZALUTAMIDE | SHILPA MEDICARE LIMITED (IN) | 2017-07-06 | — | — | US | claimed |
| EP-3168214-A1 | SUBSTITUTED 2-THIOXO-IMIDAZOLIDIN-4-ONES AND SPIRO ANALOGUES THEREOF, ACTIVE ANTI-CANCER INGREDIENT, PHARMACEUTICAL COMPOSITION, MEDICINAL PREPARATION, METHOD FOR TREATING PROSTATE CANCER | R-PHHARM OVERSEAS INK. (US) | 2017-05-17 | — | — | EP | claimed |
| EP-3166931-A1 | AN IMPROVED PROCESS FOR THE PREPARATION OF ENZALUTAMIDE | Shilpa Medicare Limited (IN) | 2017-05-17 | — | — | EP | claimed |
| CN-105936633-A | 5-(3-isopropyl benzisoxazol)pyrazin-2-amine and preparation method thereof | 广东环境保护工程职业学院 | 2016-09-14 | — | — | CN | claimed |
| CN-105753802-A | 3-isopropyl-6-bromine benzisoxazole and preparing method thereof | 广东环境保护工程职业学院 | 2016-07-13 | — | — | CN | claimed |
| WO-2016005875-A1 | AN IMPROVED PROCESS FOR THE PREPARATION OF ENZALUTAMIDE | SHILPA MEDICARE LIMITED (IN) | 2016-01-14 | — | — | WO | claimed |
| CN-101543943-B | Leadless rosin core low-halogen no-clean scaling powder and method for preparing same | YUNNAN TIN COMPANY GROUP HOLDING CO LTD | 2012-07-11 | — | — | CN | claimed |
| CN-101543943-A | Leadless rosin core low-halogen no-clean scaling powder and method for preparing same | YUNNAN TIN COMPANY GROUP HOLDI | 2009-09-30 | — | — | CN | claimed |
| EP-1377589-B1 | OXAZOLYL-PYRAZOLE DERIVATIVES AS KINASE INHIBITORS | PHARMACIA ITALIA SPA (IT) | 2005-09-07 | — | — | EP | claimed |