Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | GLA | P06280 | 1/20 | 0.59 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.52 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.50 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.50 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.50 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.50 |
| ▸ | MYC | P01106 | 1/20 | 0.49 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.49 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.47 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.47 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.47 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.47 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.47 |
| ▸ | CES2 | O00748 | 2/20 | 0.47 |
| ▸ | GALR3 | O60755 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2554 | 1.00 | KDM4E (0.59) | KDM4EGLADGAT1AKR1C2AKR1C1 | |
| SCHEMBL875504 | 0.83 | ALDH1A1 (0.53) | KDM4EGLADGAT1AKR1C2AKR1C1 | |
| SCHEMBL156346 | 0.83 | DGAT1 (0.68) | KDM4EGLADGAT1MYCNR4A1 | |
| SCHEMBL3652414 | 0.81 | AKR1C3 (0.54) | KDM4EGLAAKR1C2AKR1C1AKR1C3 | |
| SCHEMBL10082 | 0.81 | DGAT1 (0.50) | KDM4EGLADGAT1MYCNR4A1 | |
| Hydrochloric Acid SCHEMBL2349044 | 0.81 | DGAT1 (0.66) | KDM4EGLADGAT1MYCNR4A1 | |
| SCHEMBL181200 | 0.81 | ALDH1A1 (0.52) | KDM4EGLADGAT1AKR1C2AKR1C1 | |
| SCHEMBL29401981 | 0.81 | ALDH1A1 (0.52) | KDM4EGLADGAT1AKR1C2AKR1C1 | |
| SCHEMBL30374539 | 0.81 | DGAT1 (0.50) | KDM4EGLADGAT1MYCNR4A1 | |
| SCHEMBL351693 | 0.81 | DGAT1 (0.71) | KDM4EGLADGAT1CES2GALR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4536653-A2 | SIALIC ACID DERIVATIVES AND METHODS OF USING SAME | Eisai R&D Management Co., Ltd. (JP) | 2025-04-16 | — | — | EP | disclosed |
| WO-2024020522-A1 | COMPOUNDS AND METHODS FOR THE TARGETED DEGRADATION OF IRAK-4 | ARVINAS OPERATIONS, INC. (US) | 2024-01-25 | — | — | WO | disclosed |
| WO-2023239906-A2 | SIALIC ACID DERIVATIVES AND METHODS OF USING SAME | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2023-12-14 | — | — | WO | disclosed |