Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 1/20 | 0.57 |
| ▸ | IAPP | P10997 | 5/20 | 0.56 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL691674 | 1.00 | ERN1 (0.57) | ERN1IAPPAKR1C3POLBGAA | |
| SCHEMBL208434 | 0.85 | AKR1C3 (0.59) | IAPPAKR1C3MAPTLMNACA1 | |
| SCHEMBL1137305 | 0.85 | AKR1C3 (0.59) | IAPPAKR1C3MAPTLMNACA1 | |
| SCHEMBL3422780 | 0.84 | AKR1C3 (0.48) | ERN1IAPPAKR1C3MAPTLMNA | |
| SCHEMBL1094265 | 0.84 | AKR1C3 (0.48) | ERN1IAPPAKR1C3MAPTLMNA | |
| SCHEMBL8669956 | 0.81 | ERN1 (0.55) | ERN1IAPPAKR1C3POLBGAA | |
| Phenol SCHEMBL4607887 | 0.80 | AKR1C3 (0.53) | AKR1C3MAPTLMNATDP1CA1 | |
| SCHEMBL8746671 | 0.80 | AKR1C3 (0.68) | AKR1C3MAPTLMNAKDM4EAPEX1 | |
| SCHEMBL31666241 | 0.80 | AKR1C3 (0.68) | AKR1C3MAPTLMNAKDM4EAPEX1 | |
| SCHEMBL3893886 | 0.80 | AKR1C3 (0.68) | AKR1C3MAPTLMNAKDM4EAPEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1173878-B1 | PROBES FOR A GAS PHASE ION SPECTROMETER | BIO RAD LABORATORIES (US) | 2011-04-06 | — | — | EP | claimed |
| EP-0649063-B1 | Matted radiation-sensitive recording material | AGFA GEVAERT AG (DE) | 1997-01-29 | — | — | EP | disclosed |
| EP-0649063-A1 | Matted radiation-sensitive recording material | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-04-19 | — | — | EP | disclosed |