Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 1/20 | 0.55 |
| ▸ | IAPP | P10997 | 4/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | FYN | P06241 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
| ▸ | MMP8 | P22894 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7607193 | 0.83 | NFKB1 (0.53) | ALDH1A1HPGDCA1CA2LMNA | |
| SCHEMBL1563517 | 0.81 | ERN1 (0.57) | ERN1IAPPPOLBGAARAB9A | |
| SCHEMBL18306421 | 0.81 | KDM4E (0.42) | ERN1GAARAB9AALDH1A1HPGD | |
| SCHEMBL691674 | 0.81 | ERN1 (0.57) | ERN1IAPPPOLBGAARAB9A | |
| SCHEMBL18306418 | 0.81 | TP53 (0.39) | ALDH1A1HSD17B10KDM4ETP53 | |
| SCHEMBL18306419 | 0.81 | ERN1 (0.58) | ERN1KDM4ETP53 | |
| SCHEMBL16287426 | 0.78 | TP53 (0.56) | CA1CA2KDM4ENFKB1CA4 | |
| SCHEMBL21457670 | 0.77 | EGFR (0.58) | ERN1RAB9AALDH1A1HPGDEGFR | |
| SCHEMBL21457666 | 0.77 | EGFR (0.58) | ERN1RAB9AALDH1A1HPGDEGFR | |
| SCHEMBL7752848 | 0.77 | TSHR (0.49) | ERN1IAPPPOLBGAARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0868905-A2 | Method for enhancing the photostability of a dibenzoylmethane derivate with a silane benzalmalonate and method of preparation of silane bezalmalonates | L'OREAL (FR) | 1998-10-07 | — | — | EP | disclosed |