Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | EZH2 | Q15910 | 3/20 | 0.38 |
| ▸ | APLNR | P35414 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4758990 | 0.84 | RECQL (0.39) | ALOX15POLBGAAHTTTSHR | |
| Adipic Acid SCHEMBL15633992 | 0.81 | LMNA (0.44) | ALOX15GAAHTTTSHRKMT2A | |
| SCHEMBL2550513 | 0.76 | GAA (0.40) | ALOX15POLBGAAHTTTSHR | |
| SCHEMBL2550517 | 0.76 | GAA (0.40) | ALOX15POLBGAAHTTTSHR | |
| SCHEMBL4275564 | 0.76 | GAA (0.40) | ALOX15POLBGAAHTTTSHR | |
| SCHEMBL15634259 | 0.76 | POLB (0.35) | ALOX15POLBGAAHTTTSHR | |
| SCHEMBL13559125 | 0.76 | RECQL (0.40) | ALOX15POLBGAARECQLKMT2A | |
| SCHEMBL21163422 | 0.76 | RECQL (0.35) | ALOX15POLBRECQLKMT2AALDH1A1 | |
| SCHEMBL18125155 | 0.76 | RECQL (0.40) | ALOX15POLBGAARECQLKMT2A | |
| SCHEMBL16749059 | 0.76 | RECQL (0.40) | ALOX15POLBGAARECQLKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2716678-B1 | SOLID PHASE POLYMERIZATION METHOD FOR PREPARING HIGH MOLECULAR WEIGHT ALIPHATIC POLYESTER | NATUREWORKS LLC (US) | 2018-04-25 | — | — | EP | disclosed |
| US-9290616-B2 | Solid-phase polymerization method for preparing high-molecular-weight aliphatic polyester | TORAY INDUSTRIES, INC. (JP) | 2016-03-22 | — | — | US | disclosed |
| US-20140100350-A1 | SOLID-PHASE POLYMERIZATION METHOD FOR PREPARING HIGH-MOLECULAR-WEIGHT ALIPHATIC POLYESTER | TORAY INDUSTRIES, INC. (JP) | 2014-04-10 | — | — | US | disclosed |