Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.35 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.35 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.35 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5528654 | 0.86 | CHRM2 (0.44) | CHRM2CHRM4CHRM3EPHX1CHRNB2 | |
| SCHEMBL14087182 | 0.84 | — | — | |
| SCHEMBL20405610 | 0.84 | — | — | |
| SCHEMBL17892815 | 0.84 | — | — | |
| SCHEMBL818581 | 0.81 | CHRNB2 (0.42) | CHRM2CHRM4CHRM3CHRNB2CHRNA4 | |
| SCHEMBL2158225 | 0.81 | TRPA1 (0.41) | CHRM2CHRM4CHRM3EPHX1 | |
| SCHEMBL15681317 | 0.81 | CHRM2 (0.41) | CHRM2CHRM4CHRM3CYP3A4 | |
| SCHEMBL14518632 | 0.81 | CHRM2 (0.41) | CHRM2CHRM4CHRM3EPHX1CYP3A4 | |
| SCHEMBL14252585 | 0.79 | CHRM2 (0.40) | CHRM2CHRM4CHRM3EPHX1CYP3A4 | |
| SCHEMBL27013380 | 0.79 | CHRM2 (0.40) | CHRM2CHRM4CHRM3EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9556104-B2 | Process for hydrogenation of esters of aromatic carboxylic acids to yield saturated homologues thereof | POLYNT S.P.A. (IT) | 2017-01-31 | — | — | US | disclosed |
| US-20150246867-A1 | PROCESS FOR HYDROGENATION OF ESTERS OF AROMATIC CARBOXYLIC ACIDS TO YIELD SATURATED HOMOLOGUES THEREOF | POLYNT S.P.A. (IT) | 2015-09-03 | — | — | US | disclosed |
| EP-2903962-A2 | PROCESS FOR HYDROGENATION OF ESTERS OF AROMATIC CARBOXYLIC ACIDS TO YIELD SATURATED HOMOLOGUES THEREOF, NEW USES FOR SAID HOMOLOGUES, AND NEW PLASTICIZED POLYMERIC MIXTURES | POLYNT S.P.A. (IT) | 2015-08-12 | — | — | EP | disclosed |
| WO-2014053535-A2 | PROCESS FOR HYDROGENATION OF ESTERS OF AROMATIC CARBOXYLIC ACIDS TO YIELD SATURATED HOMOLOGUES THEREOF, NEW USES FOR SAID HOMOLOGUES, AND NEW PLASTICIZED POLYMERIC MIXTURES | POLYNT S.P.A. (IT) | 2014-04-10 | — | — | WO | disclosed |