SCHEMBL156363

SCHEMBL156363

CC(C)(C)OC(=O)N1CCC2(CC1)CO2

nearest known ligand 0.56

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
USP2 O75604 1/20 0.56
SMN1; SMN2 Q16637 1/20 0.56
GPR119 Q8TDV5 6/20 0.46
RECQL P46063 1/20 0.45
HPGD P15428 1/20 0.44
EPHX2 P34913 1/20 0.43
EPHX1 P07099 1/20 0.42
SCD5 Q86SK9 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1700547 0.97 USP2 (0.53) USP2SMN1; SMN2GPR119RECQLHPGD
SCHEMBL1967958 0.94 USP2 (0.50) USP2SMN1; SMN2GPR119RECQLHPGD
SCHEMBL8782075 0.91 HPGD (0.51) USP2SMN1; SMN2GPR119RECQLHPGD
SCHEMBL30984754 0.90 USP2 (0.50) USP2SMN1; SMN2GPR119RECQLHPGD
SCHEMBL1222835 0.90 USP2 (0.49) USP2SMN1; SMN2GPR119RECQLHPGD
SCHEMBL6095906 0.89 USP2 (0.53) USP2SMN1; SMN2GPR119RECQLHPGD
SCHEMBL18053621 0.88 USP2 (0.59) USP2SMN1; SMN2GPR119RECQLHPGD
SCHEMBL27301651 0.87 USP2 (0.50) USP2SMN1; SMN2GPR119RECQLHPGD
SCHEMBL5539453 0.86 CHRM2 (0.50) USP2SMN1; SMN2GPR119EPHX2
SCHEMBL22814520 0.84 USP2 (0.47) USP2SMN1; SMN2GPR119RECQLHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1124 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4682148-A2 APOPTOSIS-INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE AND AUTOIMMUNE DISEASES AbbVie Ireland Unlimited Company (IE) 2026-01-21 EP claimed
US-20220315555-A1 APOPTOSIS INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE AND AUTOIMMUNE DISEASES ABBVIE INC. (US) 2022-10-06 US claimed
US-20210221789-A1 APOPTOSIS INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE AND AUTOIMMUNE DISEASES ABBVIE INC (US) 2021-07-22 US claimed
CN-122070277-A Androgen receptor PROTAC 葛兰素史密斯克莱知识产权发展有限公司 2026-05-19 CN disclosed
EP-4709720-A1 INHIBITORS AND DEGRADERS OF PIP4K PROTEIN Larkspur Biosciences, Inc. (US) 2026-03-18 EP disclosed
US-12577231-B2 Androgen receptor PROTACS GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) 2026-03-17 US disclosed
EP-4705293-A1 SPIRO-HETEROCYCLIC INHIBITORS OF KRAS G12C MUTANT PROTEINS AND USES THEREOF Amgen Inc. (US) 2026-03-11 EP disclosed
US-12559506-B2 Indazole based compounds and associated methods of use ARVINAS OPERATIONS, INC. (US) 2026-02-24 US disclosed
US-12558428-B2 Heterobifunctional compounds and their use in treating disease HALDA THERAPEUTICS OPCO, INC. (US) 2026-02-24 US disclosed
EP-3623372-B1 PYRROLO AND PYRAZOLOPYRIMIDINES AS UBIQUITIN-SPECIFIC PROTEASE 7 INHIBITORS VALO HEALTH INC (US) 2026-02-04 EP disclosed
US-20260028354-A1 TETRAHYDRONAPHTHALENE DERIVATIVES AS ESTROGEN RECEPTOR DEGRADERS REGENT OF THE UNIV OF MICHIGAN (US) 2026-01-29 US disclosed
US-6403595-B1 ANTICOAGULANTS TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 2002-06-11 US disclosed
US-6255322-B1 NERVOUS SYSTEM DISORDERS; ALZHEIMER'S DISEASE PFIZER INC. 2001-07-03 US disclosed
WO-2001019829-A2 PYRAZOLOPYRIMIDINES AS THERAPEUTIC AGENTS BASF AKTIENGESELLSCHAFT (DE) 2001-03-22 WO disclosed
EP-1057819-A1 PHTHALAZINE DERIVATIVES AND REMEDIES FOR ERECTILE DYSFUNCTION Eisai Co., Ltd. (JP) 2000-12-06 EP disclosed
EP-1054005-A1 SULFONAMIDE DERIVATIVES, PROCESS FOR PRODUCING THE SAME AND UTILIZATION THEREOF Takeda Chemical Industries, Ltd. (JP) 2000-11-22 EP disclosed
US-6048878-A Substituted piperidine derivatives as selective agonists of 5-HT receptors MERCK SHARP & DOHME LTD. (GB) 2000-04-11 US disclosed
EP-0594729-A1 2-(4-HYDROXYPIPERIDINO)-1-ALKANOL DERIVATIVES AS ANTIISCHEMIC AGENTS PFIZER INC. (US) 1994-05-04 EP disclosed
WO-1993014084-A2 PIPERIDINE DERIVATIVES GLAXO GROUP LIMITED (GB) 1993-07-22 WO disclosed
WO-1993002052-A1 2-(4-HYDROXYPIPERIDINO)-1-ALKANOL DERIVATIVES AS ANTIISCHEMIC AGENTS PFIZER INC. (US) 1993-02-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12559506-B2 Indazole based compounds and associated methods of use LRRK2, CRBN, CLK2 USP2 100/4885SMN1; SMN2 1087/4885GPR119 2190/4885
US-12558428-B2 Heterobifunctional compounds and their use in treating disease BRCA1, H1-0, FOXM1 USP2 4440/4885SMN1; SMN2 791/4885GPR119 2252/4885
US-20260028354-A1 TETRAHYDRONAPHTHALENE DERIVATIVES AS ESTROGEN RECEPTOR DEGRADERS ESRRA, ESR2, ESRRB USP2 1857/4885SMN1; SMN2 2810/4885GPR119 602/4885
US-20210221789-A1 APOPTOSIS INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE AND AUTOIMMUNE DISEASES BCL2, BAX, BCL3 USP2 1141/4885SMN1; SMN2 2670/4885GPR119 3001/4885
US-20220315555-A1 APOPTOSIS INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE AND AUTOIMMUNE DISEASES BCL2, BAX, BCL3 USP2 1141/4885SMN1; SMN2 2670/4885GPR119 3001/4885
US-12577231-B2 Androgen receptor PROTACS AR, CRBN, PSMA3 USP2 276/4885SMN1; SMN2 4159/4885GPR119 1138/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.