SCHEMBL1222835

SCHEMBL1222835

CC(C)(C)OC(=O)N1CCC2(CO2)C1

nearest known ligand 0.49

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
USP2 O75604 1/20 0.49
SMN1; SMN2 Q16637 1/20 0.49
SCD5 Q86SK9 1/20 0.44
CYP11B2 P19099 1/20 0.43
GPR119 Q8TDV5 1/20 0.42
RECQL P46063 1/20 0.40
ACACB O00763 2/20 0.40
USP30 Q70CQ3 2/20 0.39
HPGD P15428 1/20 0.39
HDAC2 Q92769 1/20 0.38
EPHX2 P34913 1/20 0.38
CYP4F2 P78329 1/20 0.38
CYP4A11 Q02928 1/20 0.38
NR1H2 P55055 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2525714 0.90 USP2 (0.46) USP2SMN1; SMN2SCD5CYP11B2RECQL
SCHEMBL156363 0.90 USP2 (0.56) USP2SMN1; SMN2SCD5GPR119RECQL
SCHEMBL2960741 0.89 USP2 (0.51) USP2SMN1; SMN2SCD5CYP11B2GPR119
SCHEMBL1700547 0.87 USP2 (0.53) USP2SMN1; SMN2SCD5GPR119RECQL
SCHEMBL1489016 0.86 USP2 (0.50) USP2SMN1; SMN2SCD5GPR119RECQL
SCHEMBL31751733 0.84 USP2 (0.41) USP2SMN1; SMN2SCD5CYP11B2GPR119
SCHEMBL1967958 0.84 USP2 (0.50) USP2SMN1; SMN2GPR119RECQLHPGD
SCHEMBL27423987 0.83 SMN1; SMN2 (0.58) USP2SMN1; SMN2SCD5CYP11B2GPR119
SCHEMBL13452494 0.83 SMN1; SMN2 (0.61) USP2SMN1; SMN2SCD5CYP11B2RECQL
SCHEMBL34464902 0.82 USP2 (0.49) USP2SMN1; SMN2SCD5CYP11B2RECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3806853-B1 COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF DISEASES ONCO3R THERAPEUTICS BV (BE) 2026-03-18 EP disclosed
US-12358886-B2 Heterocyclic compounds for use in the treatment of cancer ARTIOS PHARMA LIMITED (GB) 2025-07-15 US disclosed
WO-2025096637-A1 SUBSTITUTED ARYL SULFONAMIDES FOR USE AS SODIUM CHANNEL INHIBITORS XENON PHARMACEUTICALS INC. (CA) 2025-05-08 WO disclosed
US-12264156-B2 Compounds and pharmaceutical compositions thereof for the treatment of diseases GALAPAGOS NV (BE) 2025-04-01 US disclosed
CN-114667167-B Heterocyclic compounds for the treatment of cancer 阿提奥斯医药有限公司 2024-12-20 CN disclosed
US-20240228446-A1 PREPARATION METHOD FOR BICYCLIC COMPOUND AND APPLICATION AS ANTIFUNGAL AGENT SHANGHAI JEMINCARE PHARMACEUTICAL CO., LTD (CN) 2024-07-11 US disclosed
EP-4317139-A1 PREPARATION METHOD FOR BICYCLIC COMPOUND AND APPLICATION AS ANTIFUNGAL AGENT Shanghai Jemincare Pharmaceuticals Co., Ltd. (CN) 2024-02-07 EP disclosed
EP-4010080-B1 HETEROCYCLIC COMPOUNDS FOR USE IN THE TREATMENT OF CANCER ARTIOS PHARMA LTD (GB) 2023-09-27 EP disclosed
EP-4010080-B1 HETEROCYCLIC COMPOUNDS FOR USE IN THE TREATMENT OF CANCER ARTIOS PHARMA LTD (GB) 2023-09-27 EP disclosed
US-20230242503-A9 HETEROCYCLIC COMPOUNDS FOR USE IN THE TREATMENT OF CANCER ARTIOS PHARMA LIMITED (GB) 2023-08-03 US disclosed
US-20110201595-A1 OXAZOLIDINYL ANTIBIOTICS ACTELION PHARMACEUTICALS LTD. (CH) 2011-08-18 US disclosed
EP-2344485-A2 OXAZOLIDINYL ANTIBIOTICS Actelion Pharmaceuticals Ltd. (CH) 2011-07-20 EP disclosed
US-20110039823-A1 OXAZOLIDINONE ANTIBIOTICS ACTELION PHARMACEUTICALS LTD (CH) 2011-02-17 US disclosed
US-20100249093-A1 Substituted Heteroarylpiperidine Derivatives As Melanocortin-4 Receptor Modulators SANTHERA PHARMACEUTICALS (SCHWEIZ) AG (CH) 2010-09-30 US disclosed
US-20100249093-A1 Substituted Heteroarylpiperidine Derivatives As Melanocortin-4 Receptor Modulators SANTHERA PHARMACEUTICALS (SCHWEIZ) AG (CH) 2010-09-30 US disclosed
WO-2010041218-A2 OXAZOLIDINYL ANTIBIOTICS ACTELION PHARMACEUTICALS LTD (CH) 2010-04-15 WO disclosed
EP-2144910-A2 OXAZOLIDINONE ANTIBIOTICS Actelion Pharmaceuticals Ltd. (CH) 2010-01-20 EP disclosed
WO-2009010299-A1 SUBSTITUTED HETEROARYLPIPERIDINE DERIVATIVES AS MELANOCORTIN-4 RECEPTOR MODULATORS SANTHERA PHARMACEUTICALS (SCHWEIZ) AG (CH) 2009-01-22 WO disclosed
US-7462600-B2 Macrolides PFIZER INC (US) 2008-12-09 US disclosed
WO-2008126034-A2 OXAZOLIDINONE ANTIBIOTICS ACTELION PHARMACEUTICALS LTD (CH) 2008-10-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240228446-A1 PREPARATION METHOD FOR BICYCLIC COMPOUND AND APPLICATION AS ANTIFUNGAL AGENT ERG28, CYP51A1, DPM1 USP2 4546/4885SMN1; SMN2 4449/4885SCD5 2776/4885
US-20110201595-A1 OXAZOLIDINYL ANTIBIOTICS OXA1L, UBE2D3, PYM1 USP2 1712/4885SMN1; SMN2 2942/4885SCD5 3163/4885
US-12264156-B2 Compounds and pharmaceutical compositions thereof for the treatment of diseases TNF, IL1A, COL1A1 USP2 4030/4885SMN1; SMN2 4676/4885SCD5 4324/4885
US-20230242503-A9 HETEROCYCLIC COMPOUNDS FOR USE IN THE TREATMENT OF CANCER SDHA, SDHB, NQO1 USP2 3720/4885SMN1; SMN2 2461/4885SCD5 1617/4885
US-20100249093-A1 Substituted Heteroarylpiperidine Derivatives As Melanocortin-4 Receptor Modulators MC4R, MC5R, MC3R USP2 3957/4885SMN1; SMN2 150/4885SCD5 724/4885
US-20110039823-A1 OXAZOLIDINONE ANTIBIOTICS OXA1L, XDH, UBE2D3 USP2 3058/4885SMN1; SMN2 3353/4885SCD5 3921/4885
US-12358886-B2 Heterocyclic compounds for use in the treatment of cancer SDHA, DPYD, TP53 USP2 3685/4885SMN1; SMN2 2897/4885SCD5 1648/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.