Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
| ▸ | BUB1 | O43683 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31283902 | 0.87 | USP2 (0.46) | USP2SMN1; SMN2RECQLGPR119HPGD | |
| SCHEMBL156363 | 0.84 | USP2 (0.56) | USP2SMN1; SMN2RECQLGPR119HPGD | |
| SCHEMBL1700547 | 0.81 | USP2 (0.53) | USP2SMN1; SMN2RECQLGPR119HPGD | |
| SCHEMBL6825314 | 0.81 | USP2 (0.41) | USP2SMN1; SMN2RECQLGPR119HPGD | |
| SCHEMBL18053621 | 0.80 | USP2 (0.59) | USP2SMN1; SMN2RECQLGPR119HPGD | |
| SCHEMBL6823515 | 0.79 | USP2 (0.40) | USP2SMN1; SMN2RECQLGPR119HPGD | |
| SCHEMBL3436829 | 0.79 | USP2 (0.56) | USP2SMN1; SMN2RECQLGPR119HPGD | |
| SCHEMBL27301651 | 0.79 | USP2 (0.50) | USP2SMN1; SMN2RECQLGPR119HPGD | |
| SCHEMBL1967958 | 0.79 | USP2 (0.50) | USP2SMN1; SMN2RECQLGPR119HPGD | |
| SCHEMBL1222835 | 0.78 | USP2 (0.49) | USP2SMN1; SMN2RECQLGPR119HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3753941-A1 | PYRIMIDINE-FUSED CYCLIC COMPOUND, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | Shanghai Blueray Biopharma Co., Ltd. (CN) | 2020-12-23 | — | — | EP | disclosed |