Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15637084 | 0.91 | THRB (0.40) | SMN1; SMN2CYP3A4 | |
| SCHEMBL15637208 | 0.91 | THRB (0.40) | SMN1; SMN2CYP3A4 | |
| SCHEMBL15637724 | 0.79 | TSHR (0.38) | L3MBTL1KDM4ENLRP3KMT2ALMNA | |
| SCHEMBL15636759 | 0.78 | ALDH1A1 (0.35) | L3MBTL1KDM4ENLRP3SMN1; SMN2MAPT | |
| SCHEMBL15637310 | 0.77 | KDM4E (0.34) | L3MBTL1KDM4EKMT2AMEN1LMNA | |
| Hydrochloric Acid SCHEMBL15637577 | 0.76 | MAPT (0.49) | L3MBTL1LMNASMN1; SMN2MAPT | |
| SCHEMBL15637349 | 0.75 | SMN1; SMN2 (0.37) | L3MBTL1KDM4ENLRP3KMT2AMEN1 | |
| SCHEMBL12559124 | 0.75 | CYP3A4 (0.44) | L3MBTL1KDM4ENLRP3KMT2AMEN1 | |
| SCHEMBL15636005 | 0.74 | KDM4E (0.33) | L3MBTL1KDM4EKMT2AMEN1LMNA | |
| SCHEMBL20636994 | 0.74 | NPSR1 (0.40) | L3MBTL1KDM4EKMT2AMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3508489-B1 | A PROCESS FOR THE PREPARATION OF ACYLPHOSPHANES | ETH ZUERICH (CH) | 2021-04-14 | — | — | EP | claimed |
| EP-3508489-A1 | A PROCESS FOR THE PREPARATION OF ACYLPHOSPHANES | ETH Zürich (CH) | 2019-07-10 | — | — | EP | claimed |
| US-9701700-B2 | Process for the preparation of acylphosphanes | ETH ZUERICH (CH) | 2017-07-11 | — | — | US | claimed |
| US-20150299231-A1 | A PROCESS FOR THE PREPARATION OF ACYLPHOSPHANES | ETH ZUERICH (CH) | 2015-10-22 | — | — | US | claimed |
| EP-2903995-A1 | A PROCESS FOR THE PREPARATION OF ACYLPHOSPHANES | ETH Zürich (CH) | 2015-08-12 | — | — | EP | claimed |
| WO-2014053455-A1 | A PROCESS FOR THE PREPARATION OF ACYLPHOSPHANES | ETH Zürich (CH) | 2014-04-10 | — | — | WO | claimed |
| EP-3508489-B1 | A PROCESS FOR THE PREPARATION OF ACYLPHOSPHANES | ETH ZUERICH (CH) | 2021-04-14 | — | — | EP | disclosed |
| EP-3508489-A1 | A PROCESS FOR THE PREPARATION OF ACYLPHOSPHANES | ETH Zürich (CH) | 2019-07-10 | — | — | EP | disclosed |
| US-10273258-B2 | Process for the preparation of acylphosphanes | ETH ZUERICH (CH) | 2019-04-30 | — | — | US | disclosed |
| US-20180002357-A1 | PROCESS FOR THE PREPARATION OF ACYLPHOSPHANES | ETH ZUERICH (CH) | 2018-01-04 | — | — | US | disclosed |
| US-9701700-B2 | Process for the preparation of acylphosphanes | ETH ZUERICH (CH) | 2017-07-11 | — | — | US | disclosed |
| US-20150299231-A1 | A PROCESS FOR THE PREPARATION OF ACYLPHOSPHANES | ETH ZUERICH (CH) | 2015-10-22 | — | — | US | disclosed |
| EP-2903995-A1 | A PROCESS FOR THE PREPARATION OF ACYLPHOSPHANES | ETH Zürich (CH) | 2015-08-12 | — | — | EP | disclosed |
| WO-2014053455-A1 | A PROCESS FOR THE PREPARATION OF ACYLPHOSPHANES | ETH Zürich (CH) | 2014-04-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10273258-B2 | Process for the preparation of acylphosphanes | AGPAT5, AGPAT2, PHOSPHO1 | L3MBTL1 4224/4885KDM4E 2609/4885NLRP3 4849/4885 |
| US-20180002357-A1 | PROCESS FOR THE PREPARATION OF ACYLPHOSPHANES | AGPAT5, AGPAT2, PHOSPHO1 | L3MBTL1 4224/4885KDM4E 2609/4885NLRP3 4849/4885 |
| US-20150299231-A1 | A PROCESS FOR THE PREPARATION OF ACYLPHOSPHANES | AGPAT5, PHOSPHO1, AGPAT2 | L3MBTL1 4172/4885KDM4E 2878/4885NLRP3 4868/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.