SCHEMBL1563701

SCHEMBL1563701

C/C(CC(C)C)=N/NC(=O)C(C)C

nearest known ligand 0.50

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 2/20 0.50
TDP1 Q9NUW8 4/20 0.41
ALDH1A1 P00352 2/20 0.41
LMNA P02545 1/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
MAPT P10636 3/20 0.34
MAPK1 P28482 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
CA2 P00918 1/20 0.33
KDM4E B2RXH2 4/20 0.32
POLB P06746 1/20 0.32
GAA P10253 1/20 0.31
PKM P14618 1/20 0.31
MAOA P21397 1/20 0.31
MAOB P27338 1/20 0.31
KISS1R Q969F8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1563703 1.00 RAB9A (0.50) RAB9ATDP1ALDH1A1LMNASMN1; SMN2
SCHEMBL6633190 1.00 RAB9A (0.50) RAB9ATDP1ALDH1A1LMNASMN1; SMN2
SCHEMBL1562182 0.81 ALDH1A1 (0.37) RAB9ATDP1ALDH1A1LMNASMN1; SMN2
SCHEMBL1562184 0.81 ALDH1A1 (0.37) RAB9ATDP1ALDH1A1LMNASMN1; SMN2
SCHEMBL6638403 0.81 ALDH1A1 (0.37) RAB9ATDP1ALDH1A1LMNASMN1; SMN2
SCHEMBL1563619 0.78 RAB9A (0.49) RAB9ATDP1ALDH1A1LMNASMN1; SMN2
SCHEMBL1563618 0.78 RAB9A (0.49) RAB9ATDP1ALDH1A1LMNASMN1; SMN2
SCHEMBL6637471 0.78 RAB9A (0.49) RAB9ATDP1ALDH1A1LMNASMN1; SMN2
SCHEMBL18222974 0.76 KDM4E (0.49) RAB9ATDP1ALDH1A1LMNASMN1; SMN2
SCHEMBL18222975 0.76 KDM4E (0.49) RAB9ATDP1ALDH1A1LMNASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9556351-B2 Rubber composition suitable for use as a cap ply in a tire Bridgestone Americas Tire Operations, Inc. (US) 2017-01-31 US disclosed
US-20160040024-A1 RUBBER COMPOSITION SUITABLE FOR USE AS A CAP PLY IN A TIRE BRIDGESTONE AMERICAS TIRE OPERATIONS, LLC 2016-02-11 US disclosed
US-9163127-B2 Rubber composition suitable for use as a cap ply in a tire BRIDGESTONE AMERICAS TIRE OPERATIONS, LLC (US) 2015-10-20 US disclosed
US-20140005320-A1 RUBBER COMPOSITION SUITABLE FOR USE AS A CAP PLY IN A TIRE BRIDGESTONE AMERICAS TIRE OPERATIONS, LLC (US) 2014-01-02 US disclosed
EP-2665771-A2 A RUBBER COMPOSITION SUITABLE FOR USE AS A CAP PLY IN A TIRE Bridgestone Americas Tire Operations, LLC (US) 2013-11-27 EP disclosed
WO-2012099955-A2 A RUBBER COMPOSITION SUITABLE FOR USE AS A CAP PLY IN A TIRE BRIDGESTONE AMERICAS TIRE OPERATIONS, LLC (US) 2012-07-26 WO disclosed
EP-1475408-B1 RUBBER COMPOSITION AND PNEUMATIC TIRE MADE THEREFROM BRIDGESTONE CORP (JP) 2011-04-06 EP disclosed
EP-1083199-B1 RUBBER COMPOSITION AND PNEUMATIC TIRE BRIDGESTONE CORP (JP) 2006-08-02 EP disclosed
US-20050176858-A1 Rubber composition and pneumatic tire made therefrom BRIDGESTONE CORPORATION 2005-08-11 US disclosed
EP-1184412-B1 Rubber composition and heavy duty pneumetic tire using the rubber composition BRIDGESTONE CORP (JP) 2005-01-12 EP disclosed
US-6822027-B2 MODIFIED STYRENE-BUTADIENE COPOLYMER RUBBER THAT HAS A TIN ATOM, NATURAL RUBBER OR SYNTHETIC ISOPRENE RUBBERS, AND A HYDRAZIDE COMPOUND. BRIDGESTONE CORPORATION (JP) 2004-11-23 US disclosed
EP-1475408-A1 RUBBER COMPOSITION AND PNEUMATIC TIRE MADE THEREFROM Bridgestone Corporation (JP) 2004-11-10 EP disclosed
US-6506849-B1 Natural or synthetic rubber; maleimide compound; and polyaniline, hydrazide and/or amine compound; workability, elasticity BRIDGESTONE CORPORATION (JP) 2003-01-14 US disclosed
US-20020049294-A1 Rubber composition and heavy duty pneumatic tire using the rubber composition BRIDGESTONE CORPORATION 2002-04-25 US disclosed
EP-1184412-A1 Rubber composition and heavy duty pneumetic tire using the rubber composition Bridgestone Corporation (JP) 2002-03-06 EP disclosed