Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.38 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.38 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.38 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.36 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.36 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 2/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.36 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.35 |
| ▸ | NAAA | Q02083 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Valine SCHEMBL5401541 | 0.86 | SLC7A5 (0.56) | SLC7A5GRIK1GRIK2SLC1A2SLC1A1 | |
| Valine SCHEMBL4045692 | 0.85 | SLC7A5 (0.71) | SLC7A5SMN1; SMN2GRIK1GRIK2SLC1A2 | |
| Valine SCHEMBL8726713 | 0.84 | SLC7A5 (0.54) | SLC7A5GRIK1GRIK2TSHRACE2 | |
| Dodecane SCHEMBL28109673 | 0.83 | SLC7A5 (0.68) | SLC7A5GRIK1GRIK2SLC1A2SLC1A1 | |
| Valine SCHEMBL11005807 | 0.83 | SLC7A5 (0.68) | SLC7A5GRIK1GRIK2SLC1A2SLC1A1 | |
| Valine SCHEMBL9355634 | 0.83 | SLC7A5 (0.52) | SLC7A5GRIK1GRIK2SLC1A2SLC1A1 | |
| Valine SCHEMBL28555130 | 0.78 | SLC7A5 (0.60) | SLC7A5GRIK1GRIK2SLC1A2SLC1A1 | |
| Valine SCHEMBL11876966 | 0.77 | SLC7A5 (0.79) | SLC7A5GRIK1GRIK2SLC1A2SLC1A1 | |
| Tetrabuthylammonium SCHEMBL18878889 | 0.77 | SLC7A5 (0.58) | SLC7A5SMN1; SMN2GRIK1GRIK2SLC1A2 | |
| Tetrabuthylammonium SCHEMBL18878892 | 0.77 | SLC7A5 (0.58) | SLC7A5SMN1; SMN2GRIK1GRIK2SLC1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140100255-A1 | Novel Compounds As Antagonists Or Inverse Agonists At Opioid Receptors | GLAXOSMITHKLINE LLC (US) | 2014-04-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140100255-A1 | Novel Compounds As Antagonists Or Inverse Agonists At Opioid Receptors | OPRL1, OPRM1, OPRK1 | SLC7A5 1950/4885SMN1; SMN2 1774/4885GRIK1 324/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.