SCHEMBL1565415

SCHEMBL1565415

O=C1CC2C=CC(C1)O2

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1701972 0.70
SCHEMBL19276036 0.70
SCHEMBL14515460 0.65
SCHEMBL8348752 0.65
SCHEMBL8013606 0.65 MAPK1 (0.31)
SCHEMBL3246775 0.65
SCHEMBL31263224 0.64
SCHEMBL8073612 0.63
SCHEMBL622881 0.61
SCHEMBL7861857 0.61

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 74 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4709719-A1 5-CYANO-1H-IMIDAZOLE-2-CARBOXAMIDE COMPOUNDS AS CSF1R INHIBITORS Modulo Bio, Inc. (US) 2026-03-18 EP disclosed
WO-2024254440-A1 5-CYANO-1H-IMIDAZOLE-2-CARBOXAMIDE COMPOUNDS AS CSF1R INHIBITORS MODULO BIO, INC. (US) 2024-12-12 WO disclosed
US-12054493-B2 Hepatitis B antiviral agents ENANTA PHARMACEUTICALS, INC. (US) 2024-08-06 US disclosed
EP-3426245-B1 HEPATITIS B ANTIVIRAL AGENTS ENANTA PHARM INC (US) 2022-12-14 EP disclosed
EP-3208269-B1 INHIBITORS OF C-FMS KINASE JANSSEN PHARMACEUTICA NV (BE) 2021-09-15 EP disclosed
US-20210230176-A1 HEPATITIS B ANTIVIRAL AGENTS ENANTA PHARM INC (US) 2021-07-29 US disclosed
US-10934306-B2 Hepatitis B antiviral agents ENANTA PHARMACEUTICALS, INC. (US) 2021-03-02 US disclosed
US-20200199143-A1 HEPATITIS B ANTIVIRAL AGENTS ENANTA PHARM INC (US) 2020-06-25 US disclosed
US-20190084994-A1 HEPATITIS B ANTIVIRAL AGENTS ENANTA PHARM INC (US) 2019-03-21 US disclosed
EP-3426245-A1 HEPATITIS B ANTIVIRAL AGENTS Enanta Pharmaceuticals, Inc. (US) 2019-01-16 EP disclosed
WO-1994005657-A1 HETEROARYLNAPHTHALENE HYDROXY ACIDS AS INHIBITORS OF LEUKOTRIENE BIOSYNTHESIS MERCK FROSST CANADA INC. (CA) 1994-03-17 WO disclosed
US-5281720-A Antiasthmatics, antiallergens, antiinflammatory agents and cytoprotective agents MERCK FROSST CANADA, INC. 1994-01-25 US disclosed
US-5252599-A Antiasthma, antiallergens, antiinflammatory agents MERCK FROSST CANADA, INC. (CA) 1993-10-12 US disclosed
US-5227399-A Pyranylphenyl naphthalene lactones as inhibitors of leukotriene biosynthesis MERCK FROSST CANADA, INC. (CA) 1993-07-13 US disclosed
EP-0501579-A1 Naphthalene lactones as inhibitors of leukotriene biosynthesis MERCK FROSST CANADA INC. (CA) 1992-09-02 EP disclosed
EP-0501578-A1 Pyranylphenyl hydroxyalkylnaphthoic acids as inhibitors of leukotriene biosynthesis MERCK FROSST CANADA INC. (CA) 1992-09-02 EP disclosed
US-4670041-A PLANT GROWTH REGULATORS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1987-06-02 US disclosed
US-4567283-A EPOXYCYCLOHEXANOLS SHELL OIL COMPANY (US) 1986-01-28 US disclosed
US-4554366-A HERBICIDES, PLANT GROWTH REGULATORS SHELL OIL COMPANY (US) 1985-11-19 US disclosed
US-4542244-A Oxabicycloalkane herbicides SHELL OIL COMPANY (US) 1985-09-17 US disclosed