Desmosterol

Desmosterol

SCHEMBL156561

CC(C)=CCC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ RORC P51449 3/20 1.00
▸ GRIN1 Q05586 6/20 0.77
▸ GRIN2A Q12879 6/20 0.77
▸ GRIN2B Q13224 5/20 0.77
▸ OSBP P22059 5/20 0.75
▸ OSBP2 Q969R2 2/20 0.75
▸ USP2 O75604 1/20 0.75
▸ LMNA P02545 1/20 0.75
▸ ABCB1 P08183 1/20 0.75
▸ CYP46A1 Q9Y6A2 1/20 0.75
▸ DHCR24 Q15392 1/20 0.74
▸ NR1H3 Q13133 7/20 0.74
▸ EPHA2 P29317 1/20 0.73
▸ NR1H2 P55055 1/20 0.72
▸ TSHR P16473 1/20 0.72
▸ TDP1 Q9NUW8 1/20 0.72

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Desmosterol SCHEMBL26641636 1.00 RORC (1.00) RORCGRIN1GRIN2AGRIN2BOSBP
Desmosterol SCHEMBL12917612 1.00 RORC (1.00) RORCGRIN1GRIN2AGRIN2BOSBP
Desmosterol SCHEMBL18942512 1.00 RORC (1.00) RORCGRIN1GRIN2AGRIN2BOSBP
Desmosterol SCHEMBL13833045 1.00 RORC (1.00) RORCGRIN1GRIN2AGRIN2BOSBP
Desmosterol SCHEMBL288290 1.00 RORC (1.00) RORCGRIN1GRIN2AGRIN2BOSBP
Desmosterol SCHEMBL23565992 1.00 RORC (1.00) RORCGRIN1GRIN2AGRIN2BOSBP
Desmosterol SCHEMBL2154711 1.00 RORC (1.00) RORCGRIN1GRIN2AGRIN2BOSBP
Desmosterol SCHEMBL288400 1.00 RORC (1.00) RORCGRIN1GRIN2AGRIN2BOSBP
Desmosterol SCHEMBL288990 1.00 RORC (1.00) RORCGRIN1GRIN2AGRIN2BOSBP
Desmosterol SCHEMBL19507013 1.00 RORC (1.00) RORCGRIN1GRIN2AGRIN2BOSBP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 4493 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4747627-A1 METHODS AND SYSTEMS FOR PREDICTIVE CLASSIFICATION BY MASS SPECTROMETRY AND TRAINED LARGE SPECTRAL MODELS Matterworks Inc (US) 2026-05-27 — — EP claimed
US-20260139254-A1 INTERFERING RNA FOR INHIBITING TOP1 GENE EXPRESSION AND USE THEREOF JENKEM TECH CO LTD BEIJING (CN) 2026-05-21 — — US claimed
WO-2026090590-A1 NANOPARTICLE FORMULATIONS FOR THE DELIVERY OF DNA TO ADIPOSE TISSUE Remedium Bio, Inc. (US) 2026-04-30 — — WO claimed
US-20260108622-A1 NON-PEGYLATED LIPID NANOPARTICLES MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2026-04-23 — — US claimed
EP-4721759-A1 LIPID NANOPARTICLE FOR DELIVERING NUCLEIC ACID DRUG, AND PREPARATION METHOD THEREFOR AND USE THEREOF Cansino (Shanghai) Biological Research Co., Ltd. (CN) 2026-04-08 — — EP claimed
EP-4707289-A1 STEROID-CATIONIC LIPID COMPOUND AND USE THEREOF Cansino (Shanghai) Biological Research Co., Ltd. (CN) 2026-03-11 — — EP claimed
EP-4706644-A1 RECONSTITUTED HIGH-DENSITY LIPOPROTEIN NANOPARTICLES COMPRISING CHOLESTEROL Mepsgen Co., Ltd. (KR) 2026-03-11 — — EP claimed
EP-4342929-B1 POLYETHYLENE GLYCOL LIPID AND USE THEREOF JENKEM TECH CO LTD TIANJIN (CN) 2026-02-04 — — EP claimed
US-20260009064-A1 STEROL PRODUCTION IN YEAST Apix Biosciences (BE) 2026-01-08 — — US claimed
EP-4365168-B1 POLYOL-MODIFIED LIPID COMPOUND AND PREPARATION METHOD AND APPLICATION THEREOF JENKEM TECH CO LTD TIANJIN (CN) 2025-10-15 — — EP claimed
EP-0465343-A1 Pharmaceutical or cosmetical composition comprising a retinoid and a sterol in association CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA - CIRD GALDERMA (FR) 1992-01-08 — — EP claimed
US-5043329-A Methods and compositions employing unique mixtures of polar and neutral lipids for protecting the gastrointestinal tract BOARD OF REGENTS, UNIVERSITY OF TEXAS SYSTEM (US) 1991-08-27 — — US claimed
EP-0406998-A2 Use of phospholipids in lung surfactant replacement therapy BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 1991-01-09 — — EP claimed
EP-0401952-A2 Use of phospholipids in lung surfactant replacement therapy BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 1990-12-12 — — EP claimed
EP-0287198-A2 Mixtures of polar and neutral lipids for protecting the gastronointestinal tract BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 1988-10-19 — — EP claimed
US-4687744-A INCUBATING ZOOSPORES WITH STEROL AND FATTY ACID MEDIUM THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1987-08-18 — — US claimed
EP-0190442-A1 Process for the preparation of C7-hydroxylated cholesterol and desmosterol "HARRIER" GMBH GESELLSCHAFT FÜR DEN VERTRIEB MEDIZINISCHER UND TECHNISCHER GERÄTE (DE) 1986-08-13 — — EP claimed
EP-0005653-B1 PROCESS FOR THE PREPARATION OF 24,25-DIHYDROXY-CHOLESTEROL FROM DESMOSTEROL ETAT DU CAMEROUN représenté par le Ministère de l'Education Nationale (CM) 1982-07-28 — — EP claimed
EP-0005653-A1 Process for the preparation of 24,25-dihydroxy-cholesterol from desmosterol ETAT DU CAMEROUN représenté par le Ministère de l'Education Nationale (CM) 1979-11-28 — — EP claimed
US-3936478-A Process for the preparation of desmosterol derivatives TEIJIN LIMITED (JA) 1976-02-03 — — US claimed
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