Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 3/20 | 1.00 |
| ▸ | GRIN1 | Q05586 | 6/20 | 0.77 |
| ▸ | GRIN2A | Q12879 | 6/20 | 0.77 |
| ▸ | GRIN2B | Q13224 | 5/20 | 0.77 |
| ▸ | OSBP | P22059 | 5/20 | 0.75 |
| ▸ | OSBP2 | Q969R2 | 2/20 | 0.75 |
| ▸ | USP2 | O75604 | 1/20 | 0.75 |
| ▸ | LMNA | P02545 | 1/20 | 0.75 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.75 |
| ▸ | CYP46A1 | Q9Y6A2 | 1/20 | 0.75 |
| ▸ | DHCR24 | Q15392 | 1/20 | 0.74 |
| ▸ | NR1H3 | Q13133 | 7/20 | 0.74 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.73 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.72 |
| ▸ | TSHR | P16473 | 1/20 | 0.72 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Desmosterol SCHEMBL26641636 | 1.00 | RORC (1.00) | RORCGRIN1GRIN2AGRIN2BOSBP | |
| Desmosterol SCHEMBL12917612 | 1.00 | RORC (1.00) | RORCGRIN1GRIN2AGRIN2BOSBP | |
| Desmosterol SCHEMBL156561 | 1.00 | RORC (1.00) | RORCGRIN1GRIN2AGRIN2BOSBP | |
| Desmosterol SCHEMBL18942512 | 1.00 | RORC (1.00) | RORCGRIN1GRIN2AGRIN2BOSBP | |
| Desmosterol SCHEMBL13833045 | 1.00 | RORC (1.00) | RORCGRIN1GRIN2AGRIN2BOSBP | |
| Desmosterol SCHEMBL288290 | 1.00 | RORC (1.00) | RORCGRIN1GRIN2AGRIN2BOSBP | |
| Desmosterol SCHEMBL23565992 | 1.00 | RORC (1.00) | RORCGRIN1GRIN2AGRIN2BOSBP | |
| Desmosterol SCHEMBL288400 | 1.00 | RORC (1.00) | RORCGRIN1GRIN2AGRIN2BOSBP | |
| Desmosterol SCHEMBL288990 | 1.00 | RORC (1.00) | RORCGRIN1GRIN2AGRIN2BOSBP | |
| Desmosterol SCHEMBL19507013 | 1.00 | RORC (1.00) | RORCGRIN1GRIN2AGRIN2BOSBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011080184-A1 | USE OF ENDOGENOUS METABOLITES FOR EARLY DIAGNOSING SEPSIS | BIOCRATES LIFE SCIENCES AG (AT) | 2011-07-07 | — | — | WO | disclosed |