Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMD14 | O00487 | 12/20 | 0.61 |
| ▸ | COPS5 | Q92905 | 8/20 | 0.61 |
| ▸ | STAMBP | O95630 | 13/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | CFTR | P13569 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15660953 | 0.84 | MEN1 (0.51) | PSMD14COPS5MEN1KMT2A | |
| SCHEMBL15961574 | 0.77 | PSMD14 (1.00) | PSMD14COPS5STAMBP | |
| SCHEMBL15961579 | 0.76 | PSMD14 (1.00) | PSMD14COPS5STAMBP | |
| SCHEMBL7793486 | 0.76 | KMT2A (0.50) | MEN1KMT2ACFTR | |
| SCHEMBL7802352 | 0.75 | KMT2A (0.49) | COPS5STAMBPMEN1KMT2ACFTR | |
| SCHEMBL15659195 | 0.74 | PSMD14 (0.61) | PSMD14MEN1KMT2A | |
| SCHEMBL18526855 | 0.73 | PSMD14 (1.00) | PSMD14COPS5STAMBP | |
| SCHEMBL15658472 | 0.73 | PSMD14 (0.55) | PSMD14COPS5STAMBP | |
| SCHEMBL15660196 | 0.73 | MLYCD (0.46) | PSMD14COPS5STAMBP | |
| SCHEMBL18526863 | 0.72 | PSMD14 (1.00) | PSMD14COPS5STAMBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014066506-A2 | COMPOSITIONS AND METHODS FOR JAMM PROTEIN INHIBITION | CLEAVE BIOSCIENCES, INC. (US) | 2014-05-01 | — | — | WO | claimed |