Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 10/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.49 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.49 |
| ▸ | CTRC | Q99895 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | RARA | P10276 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | MTOR | P42345 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.46 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.46 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.45 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL27525448 | 0.98 | RARB (0.53) | RARBTSHREPHX2NR1H4CTRC | |
| SCHEMBL8506562 | 0.94 | RARB (0.56) | RARBTSHRMEN1ALDH1A1RARA | |
| SCHEMBL14037607 | 0.90 | TSHR (0.55) | RARBTSHREPHX2NR1H4MEN1 | |
| SCHEMBL15662455 | 0.87 | TSHR (0.43) | RARBTSHRCTRCAKR1C2AKR1C1 | |
| SCHEMBL17198001 | 0.84 | TSHR (0.61) | TSHREPHX2NR1H4MEN1ALDH1A1 | |
| SCHEMBL15661159 | 0.83 | MAPT (0.53) | TSHRMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL850741 | 0.81 | TYR (0.61) | RARBTSHRMEN1MAPTKMT2A | |
| SCHEMBL1356425 | 0.81 | RARB (0.51) | RARBTSHRMEN1ALDH1A1RARA | |
| SCHEMBL28407110 | 0.81 | RARB (0.54) | RARBTSHREPHX2MEN1ALDH1A1 | |
| SCHEMBL7052993 | 0.81 | TSHR (0.57) | RARBTSHREPHX2NR1H4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014063199-A1 | ORGANIC COMPOUNDS | AKAAL PHARMA PTY LTD (AU) | 2014-05-01 | — | — | WO | disclosed |