SCHEMBL850741

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL27750587	0.89	KDM4E (0.53)	TYRMAPTTP53TSHRMEN1
	SCHEMBL900912	0.86	RARB (0.51)	TYRMAPTTP53TSHRRARB
	SCHEMBL20178564	0.85	AGTR1 (0.56)	TYRTP53TSHRHTTRARB
	SCHEMBL2585314	0.83	KDM4E (0.59)	MAPTTP53TSHRMEN1HTT
	SCHEMBL1356425	0.83	RARB (0.51)	MAPTTP53TSHRMEN1KMT2A
	SCHEMBL28407110	0.83	RARB (0.54)	MAPTTP53TSHRMEN1KMT2A
	SCHEMBL25220568	0.81	RARB (0.50)	MAPTTP53TSHRMEN1KMT2A
	SCHEMBL3820800	0.81	ALDH1A1 (0.51)	MAPTTP53TSHRMEN1HTT
	SCHEMBL15660720	0.81	RARB (0.54)	MAPTTP53TSHRMEN1HTT
	SCHEMBL11862179	0.81	RARB (0.53)	MAPTTP53TSHRMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.