Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAMBP | O95630 | 1/20 | 0.45 |
| ▸ | COPS5 | Q92905 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15658528 | 0.89 | PSMD14 (0.36) | STAMBPCOPS5EPHX2NAMPT | |
| SCHEMBL15661001 | 0.89 | ADORA2A (0.38) | STAMBPCOPS5NAMPT | |
| SCHEMBL15660837 | 0.88 | KMT2A (0.55) | STAMBPCOPS5KMT2AMEN1GAA | |
| SCHEMBL15661699 | 0.88 | PSMD14 (0.40) | STAMBPCOPS5KMT2ANPC1RAB9A | |
| SCHEMBL15662119 | 0.87 | HTT (0.44) | STAMBPKMT2AMEN1SMN1; SMN2BCHE | |
| SCHEMBL15661704 | 0.87 | HPGD (0.43) | STAMBPCOPS5KMT2AMEN1GAA | |
| SCHEMBL15659212 | 0.86 | APP (0.38) | STAMBPCOPS5BCHEEGLN1EPHX2 | |
| SCHEMBL15659818 | 0.79 | PSMD14 (0.38) | STAMBPCOPS5NAMPT | |
| SCHEMBL15662184 | 0.78 | CLK1 (0.42) | STAMBPBCHELMNATP53EPHX2 | |
| SCHEMBL15661706 | 0.78 | HPGD (0.54) | STAMBPCOPS5KMT2AMEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014066506-A2 | COMPOSITIONS AND METHODS FOR JAMM PROTEIN INHIBITION | CLEAVE BIOSCIENCES, INC. (US) | 2014-05-01 | — | — | WO | claimed |