Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | STAMBP | O95630 | 1/20 | 0.53 |
| ▸ | COPS5 | Q92905 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.52 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 5/20 | 0.47 |
| ▸ | RAB9A | P51151 | 5/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | NAMPT | P43490 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15661706 | 0.89 | HPGD (0.54) | KMT2AMEN1GAASTAMBPCOPS5 | |
| SCHEMBL15660836 | 0.88 | STAMBP (0.45) | KMT2AMEN1GAASTAMBPCOPS5 | |
| SCHEMBL15661700 | 0.86 | KMT2A (0.48) | KMT2AMEN1STAMBPCOPS5NPC1 | |
| SCHEMBL15661003 | 0.85 | ADORA2A (0.44) | KMT2ASTAMBPCOPS5TP53EPHX2 | |
| SCHEMBL15658527 | 0.85 | PSMD14 (0.43) | KMT2ASTAMBPCOPS5TP53EPHX2 | |
| SCHEMBL15662120 | 0.84 | HTT (0.55) | KMT2AMEN1SMN1; SMN2TP53EPHX2 | |
| SCHEMBL15659214 | 0.83 | EPHX2 (0.45) | KMT2AMEN1STAMBPCOPS5EGLN1 | |
| SCHEMBL15661879 | 0.79 | HTT (0.52) | KMT2AMEN1SMN1; SMN2TP53EPHX2 | |
| SCHEMBL15659820 | 0.78 | ADORA2A (0.44) | STAMBPCOPS5KDM4ENAMPTALDH1A1 | |
| SCHEMBL15661704 | 0.78 | HPGD (0.43) | KMT2AMEN1GAASTAMBPCOPS5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014066506-A2 | COMPOSITIONS AND METHODS FOR JAMM PROTEIN INHIBITION | CLEAVE BIOSCIENCES, INC. (US) | 2014-05-01 | — | — | WO | claimed |