Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 4/20 | 0.63 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | TLR2 | O60603 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15660413 | 1.00 | NAAA (0.63) | NAAAHDAC3HDAC1HDAC2L3MBTL1 | |
| SCHEMBL15677528 | 0.85 | NAAA (0.63) | NAAAHDAC3L3MBTL1EPHX1ALDH1A1 | |
| SCHEMBL15660766 | 0.85 | NAAA (0.63) | NAAAHDAC3L3MBTL1EPHX1ALDH1A1 | |
| SCHEMBL15657782 | 0.85 | NAAA (0.63) | NAAAHDAC3L3MBTL1EPHX1ALDH1A1 | |
| SCHEMBL15660301 | 0.85 | NAAA (0.63) | NAAAHDAC3L3MBTL1EPHX1ALDH1A1 | |
| SCHEMBL15659605 | 0.81 | ALDH1A1 (0.56) | NAAAHDAC3ALDH1A1TLR2 | |
| SCHEMBL15661633 | 0.81 | HDAC1 (0.57) | NAAAHDAC3HDAC1L3MBTL1ALDH1A1 | |
| SCHEMBL15661187 | 0.81 | HDAC1 (0.57) | NAAAHDAC3HDAC1L3MBTL1ALDH1A1 | |
| SCHEMBL15657310 | 0.81 | ALDH1A1 (0.56) | NAAAHDAC3ALDH1A1TLR2 | |
| SCHEMBL15660528 | 0.81 | ALDH1A1 (0.56) | NAAAHDAC3ALDH1A1TLR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014066613-A2 | SPHINGOLIPID METABOLITE MIMETICS | ZHEJIANG UNIVERSITY (CN) | 2014-05-01 | — | — | WO | disclosed |