Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.42 |
| ▸ | MEN1 | O00255 | 5/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 6/20 | 0.40 |
| ▸ | CASP1 | P29466 | 6/20 | 0.40 |
| ▸ | CASP7 | P55210 | 6/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.40 |
| ▸ | CLK4 | Q9HAZ1 | 4/20 | 0.40 |
| ▸ | USP2 | O75604 | 3/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 4/20 | 0.39 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3074807 | 0.80 | EGFR (0.50) | ALDH1A1KDM4ETDP1MAPTHSD17B10 | |
| SCHEMBL6666438 | 0.78 | KDM4E (0.52) | ADRB1ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL28132260 | 0.77 | KDM4E (0.50) | ADRB1ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL28335119 | 0.77 | KDM4E (0.50) | ADRB1ALDH1A1MEN1KMT2AKDM4E | |
| Hydrochloric Acid SCHEMBL6667707 | 0.77 | KDM4E (0.50) | ADRB1ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL31038714 | 0.74 | EGFR (0.44) | KDM4ECYP3A4CYP1A2ATMCYP2A6 | |
| SCHEMBL29248284 | 0.73 | TNF (0.47) | KDM4ECYP3A4CYP1A2ATMMAPK10 | |
| SCHEMBL6968376 | 0.72 | KDM4E (0.47) | ALDH1A1MEN1KMT2AKDM4EHPGD | |
| SCHEMBL28115994 | 0.71 | CYP3A4 (0.42) | ALDH1A1MEN1KMT2AKDM4EHPGD | |
| SCHEMBL29576347 | 0.70 | CYP1A2 (0.44) | ALDH1A1MEN1KMT2AKDM4ETDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014066506-A2 | COMPOSITIONS AND METHODS FOR JAMM PROTEIN INHIBITION | CLEAVE BIOSCIENCES, INC. (US) | 2014-05-01 | — | — | WO | disclosed |