Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.52 |
| ▸ | MMP2 | P08253 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | GMNN | O75496 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | MMP9 | P14780 | 1/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.52 |
| ▸ | MMP8 | P22894 | 1/20 | 0.52 |
| ▸ | CCR1 | P32246 | 1/20 | 0.52 |
| ▸ | THPO | P40225 | 1/20 | 0.52 |
| ▸ | MTOR | P42345 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | MMP13 | P45452 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28132260 | 0.98 | KDM4E (0.50) | KDM4EMAPTTDP1ALOX15MMP2 | |
| SCHEMBL28335119 | 0.98 | KDM4E (0.50) | KDM4EMAPTTDP1ALOX15MMP2 | |
| Hydrochloric Acid SCHEMBL6667707 | 0.98 | KDM4E (0.50) | KDM4EMAPTTDP1ALOX15MMP2 | |
| SCHEMBL27873922 | 0.79 | KDM4E (0.56) | KDM4EMAPTTDP1ALOX15MMP2 | |
| SCHEMBL28083058 | 0.79 | TOP2A (0.49) | KDM4EMAPTTDP1CYP3A4SMN1; SMN2 | |
| SCHEMBL2237236 | 0.79 | GLO1 (0.47) | KDM4EMAPTTDP1CYP3A4SMN1; SMN2 | |
| SCHEMBL27863584 | 0.79 | CDK5 (0.45) | KDM4EMAPTTDP1CYP3A4SMN1; SMN2 | |
| SCHEMBL15660874 | 0.78 | ADRB1 (0.43) | KDM4EMAPTTDP1TSHRCYP3A4 | |
| SCHEMBL1282008 | 0.78 | CCR1 (0.75) | KDM4EMAPTTDP1ALOX15MMP2 | |
| SCHEMBL30184687 | 0.78 | CCR1 (0.75) | KDM4EMAPTTDP1ALOX15MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110563772-B | Nickel mononuclear hydrogenase model substance and intermediate product, preparation method and application thereof | 鲁东大学 | 2022-03-15 | — | — | CN | claimed |
| CN-110563772-A | Nickel mononuclear hydrogenase model substance and intermediate product, preparation method and application thereof | 鲁东大学 | 2019-12-13 | — | — | CN | claimed |
| WO-2004022337-A1 | STABILIZED INFRARED-SENSITIVE ELEMENTS | KODAK POLYCHROME GRAPHICS GMBH (DE) | 2004-03-18 | — | — | WO | claimed |
| JP-4296751-A | — | — | None | — | — | JP | disclosed |
| JP-55108429-A | — | — | None | — | — | JP | disclosed |
| CN-110563772-B | Nickel mononuclear hydrogenase model substance and intermediate product, preparation method and application thereof | 鲁东大学 | 2022-03-15 | — | — | CN | disclosed |
| CN-110563772-B | Nickel mononuclear hydrogenase model substance and intermediate product, preparation method and application thereof | 鲁东大学 | 2022-03-15 | — | — | CN | disclosed |
| CN-110563772-A | Nickel mononuclear hydrogenase model substance and intermediate product, preparation method and application thereof | 鲁东大学 | 2019-12-13 | — | — | CN | disclosed |
| CN-110563772-A | Nickel mononuclear hydrogenase model substance and intermediate product, preparation method and application thereof | 鲁东大学 | 2019-12-13 | — | — | CN | disclosed |
| CN-103975456-B | Comprise the light-emitting device of nanostructured | 日东电工株式会社 | 2016-10-19 | — | — | CN | disclosed |
| CN-104023529-B | Use nitrogen polymer Stable Iodine compound | 朗盛德国有限责任公司 | 2016-10-12 | — | — | CN | disclosed |
| WO-2004022337-A1 | STABILIZED INFRARED-SENSITIVE ELEMENTS | KODAK POLYCHROME GRAPHICS GMBH (DE) | 2004-03-18 | — | — | WO | disclosed |
| WO-2004022337-A1 | STABILIZED INFRARED-SENSITIVE ELEMENTS | KODAK POLYCHROME GRAPHICS GMBH (DE) | 2004-03-18 | — | — | WO | disclosed |
| US-20030207889-A1 | Hydroxamic and carboxylic acid derivatives having MMP and TNF inhibitory activity | OWEN DAVID ALAN (GB) | 2003-11-06 | — | — | US | disclosed |
| US-6566384-B1 | For therapy of cancer, inflammation and inflammatory diseases, tissue degeneration, periodontal disease, ophthalmological disease, dermatological disorders, fever, cardiovascular effects, haemorrhage, coagulation and acute phase response | DARWIN DISCOVERY LTD. (GB) | 2003-05-20 | — | — | US | disclosed |
| US-6118001-A | ANTICANCER AGENT; ANTIARTHRITIC AGENT | DARWIN DISCOVERY, LTD. (GB) | 2000-09-12 | — | — | US | disclosed |
| EP-0968182-A1 | HYDROXAMIC AND CARBOXYLIC ACID DERIVATIVES HAVING MMP AND TNF INHIBITORY ACTIVITY | Darwin Discovery Limited (GB) | 2000-01-05 | — | — | EP | disclosed |
| WO-1998005635-A1 | HYDROXAMIC AND CARBOXYLIC ACID DERIVATIVES HAVING MMP AND TNF INHIBITORY ACTIVITY | DARWIN DISCOVERY LIMITED (GB) | 1998-02-12 | — | — | WO | disclosed |
| JP-H04296751-A | HEAT DEVELOPABLE COLOR PHOTOSENSITIVE MATERIAL AND IMAGE FORMING METHOD | KONICA CORP | 1992-10-21 | — | — | JP | disclosed |
| JP-S55108429-A | RUBBER COMPOSITION | JAPAN SYNTHETIC RUBBER CO LTD | 1980-08-20 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030207889-A1 | Hydroxamic and carboxylic acid derivatives having MMP and TNF inhibitory activity | MMP13, MMP2, MMP9 | KDM4E 1809/4885MAPT 3585/4885TDP1 2654/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.