Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Cefmenoxime. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 5/20 | 0.88 |
| ▸ | PGR | P06401 | 2/20 | 0.88 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.79 |
| ▸ | MAPT | P10636 | 5/20 | 0.79 |
| ▸ | APEX1 | P27695 | 3/20 | 0.79 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.79 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.79 |
| ▸ | POLB | P06746 | 2/20 | 0.79 |
| ▸ | RECQL | P46063 | 2/20 | 0.79 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.79 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.79 |
| ▸ | BLM | P54132 | 1/20 | 0.79 |
| ▸ | ABCC4 | O15439 | 2/20 | 0.70 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.70 |
| ▸ | PKM | P14618 | 1/20 | 0.70 |
| ▸ | LMNA | P02545 | 1/20 | 0.70 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.70 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.70 |
| ▸ | PPARG | P37231 | 2/20 | 0.67 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cefmenoxime SCHEMBL9074653 | 1.00 | NR1I2 (0.88) | NR1I2PGRTDP1MAPTAPEX1 | |
| Cefmenoxime SCHEMBL9074658 | 1.00 | NR1I2 (0.88) | NR1I2PGRTDP1MAPTAPEX1 | |
| Cefmenoxime SCHEMBL9651055 | 1.00 | NR1I2 (0.88) | NR1I2PGRTDP1MAPTAPEX1 | |
| Cefmenoxime SCHEMBL10776181 | 1.00 | NR1I2 (0.88) | NR1I2PGRTDP1MAPTAPEX1 | |
| Cefmenoxime SCHEMBL10776170 | 1.00 | NR1I2 (0.88) | NR1I2PGRTDP1MAPTAPEX1 | |
| SCHEMBL10832800 | 0.93 | NR1I2 (0.77) | NR1I2PGRTDP1MAPTAPEX1 | |
| Cefmenoxime SCHEMBL8768620 | 0.93 | NR1I2 (1.00) | NR1I2PGRTDP1MAPTAPEX1 | |
| Cefmenoxime SCHEMBL152861 | 0.93 | NR1I2 (1.00) | NR1I2PGRTDP1MAPTAPEX1 | |
| Cefmenoxime SCHEMBL9659869 | 0.93 | NR1I2 (1.00) | NR1I2PGRTDP1MAPTAPEX1 | |
| Cefmenoxime SCHEMBL1813696 | 0.93 | NR1I2 (1.00) | NR1I2PGRTDP1MAPTAPEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8895728-B2 | Method for preparing cefmenoxime hydrochloride compound | HAINAN LINGKANG PHARMACEUTICAL CO., LTD. (CN) | 2014-11-25 | — | — | US | disclosed |
| US-20140121370-A1 | NOVEL METHOD FOR PREPARING CEFMENOXIME HYDROCHLORIDE COMPOUND | HAINAN LINGKANG PHARMACEUTICAL CO., LTD. (CN) | 2014-05-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140121370-A1 | NOVEL METHOD FOR PREPARING CEFMENOXIME HYDROCHLORIDE COMPOUND | F7, PDE7A, NSF | NR1I2 4691/4885PGR 4819/4885TDP1 4408/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.