Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.50 |
| ▸ | LMNA | P02545 | 8/20 | 0.48 |
| ▸ | THRB | P10828 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 5/20 | 0.47 |
| ▸ | HPGD | P15428 | 4/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.47 |
| ▸ | RELA | Q04206 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 4/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17761121 | 0.84 | ALDH1A1 (0.68) | ALDH1A1LMNATHRBTSHRHPGD | |
| SCHEMBL24305911 | 0.84 | ALDH1A1 (0.68) | ALDH1A1LMNATHRBTSHRHPGD | |
| SCHEMBL16526226 | 0.83 | ALDH1A1 (0.70) | ALDH1A1LMNATHRBTSHRHPGD | |
| SCHEMBL18723118 | 0.82 | ALDH1A1 (0.59) | ALDH1A1LMNATHRBTSHRHPGD | |
| SCHEMBL17755396 | 0.81 | ALDH1A1 (0.59) | ALDH1A1LMNATHRBTSHRHPGD | |
| SCHEMBL16522420 | 0.80 | ALDH1A1 (0.61) | ALDH1A1LMNATHRBTSHRHPGD | |
| SCHEMBL16116944 | 0.80 | ALDH1A1 (0.72) | ALDH1A1LMNATHRBTSHRHPGD | |
| SCHEMBL18723001 | 0.79 | ALDH1A1 (0.58) | ALDH1A1LMNATHRBTSHRHPGD | |
| SCHEMBL15679447 | 0.79 | ALDH1A1 (0.48) | ALDH1A1LMNATSHRHPGDNPSR1 | |
| SCHEMBL15664141 | 0.79 | ALDH1A1 (0.48) | ALDH1A1LMNATSHRHPGDNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9945852-B2 | Method for determining the presence or absence of a biomarker | ARCIS BIOTECHNOLOGY HOLDINGS LIMITED (GB) | 2018-04-17 | — | — | US | disclosed |
| EP-2705367-B1 | METHOD FOR DETERMINING THE PRESENCE OR ABSENCE OF A BIOMARKER | BANGOR UNIV (GB) | 2017-04-26 | — | — | EP | disclosed |
| US-20140127709-A1 | METHOD FOR DETERMINING THE PRESENCE OR ABSENCE OF A BIOMARKER | BANGOR UNIVERSITY (GB) | 2014-05-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140127709-A1 | METHOD FOR DETERMINING THE PRESENCE OR ABSENCE OF A BIOMARKER | CA14, CD63, CA12 | ALDH1A1 1037/4885LMNA 3363/4885THRB 2385/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.