Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.48 |
| ▸ | LMNA | P02545 | 7/20 | 0.48 |
| ▸ | HTT | P42858 | 6/20 | 0.48 |
| ▸ | TP53 | P04637 | 5/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.48 |
| ▸ | HPGD | P15428 | 4/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.48 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 8/20 | 0.47 |
| ▸ | PTPRB | P23467 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15679447 | 1.00 | ALDH1A1 (0.48) | ALDH1A1LMNAHTTTP53NPSR1 | |
| SCHEMBL16218976 | 0.85 | ALDH1A1 (0.61) | ALDH1A1LMNAHTTTP53NPSR1 | |
| SCHEMBL28102527 | 0.85 | ALDH1A1 (0.61) | ALDH1A1LMNAHTTTP53NPSR1 | |
| SCHEMBL1980247 | 0.85 | ALDH1A1 (0.61) | ALDH1A1LMNAHTTTP53NPSR1 | |
| SCHEMBL17511740 | 0.84 | ALDH1A1 (0.63) | ALDH1A1LMNAHTTTP53NPSR1 | |
| SCHEMBL2966537 | 0.80 | ALDH1A1 (0.64) | ALDH1A1LMNAHTTTP53NPSR1 | |
| SCHEMBL15664164 | 0.79 | ALDH1A1 (0.50) | ALDH1A1LMNAHTTTP53NPSR1 | |
| SCHEMBL15665004 | 0.77 | PTPRB (0.43) | ALDH1A1LMNAHTTTP53NPSR1 | |
| SCHEMBL15665002 | 0.77 | PTPRB (0.43) | ALDH1A1LMNAHTTTP53NPSR1 | |
| SCHEMBL2976178 | 0.75 | ALDH1A1 (0.69) | ALDH1A1LMNAHTTTP53NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9945852-B2 | Method for determining the presence or absence of a biomarker | ARCIS BIOTECHNOLOGY HOLDINGS LIMITED (GB) | 2018-04-17 | — | — | US | disclosed |
| US-20140127709-A1 | METHOD FOR DETERMINING THE PRESENCE OR ABSENCE OF A BIOMARKER | BANGOR UNIVERSITY (GB) | 2014-05-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140127709-A1 | METHOD FOR DETERMINING THE PRESENCE OR ABSENCE OF A BIOMARKER | CA14, CD63, CA12 | ALDH1A1 1037/4885LMNA 3363/4885HTT 3270/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.