Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HINT1 | P49773 | 7/20 | 0.66 |
| ▸ | NT5E | P21589 | 1/20 | 0.58 |
| ▸ | IMPDH2 | P12268 | 6/20 | 0.57 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.56 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.56 |
| ▸ | TGM2 | P21980 | 1/20 | 0.55 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.54 |
| ▸ | GSK3A | P49840 | 1/20 | 0.54 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.54 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.54 |
| ▸ | KRAS | P01116 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| E626 SCHEMBL5365314 | 1.00 | HINT1 (0.66) | HINT1NT5EIMPDH2TAS1R3TAS1R1 | |
| E626 SCHEMBL15670356 | 0.94 | HINT1 (0.60) | HINT1NT5EIMPDH2TAS1R3TAS1R1 | |
| Guanosine SCHEMBL11034252 | 0.90 | HINT1 (0.66) | HINT1NT5EGSK3ARPS6KA3MAPK14 | |
| E626 SCHEMBL28161803 | 0.88 | NT5E (0.66) | HINT1NT5EIMPDH2TAS1R3TAS1R1 | |
| E626 SCHEMBL15670410 | 0.88 | NT5E (0.66) | HINT1NT5EIMPDH2TAS1R3TAS1R1 | |
| Adenosine Phosphate SCHEMBL15670577 | 0.87 | P2RY1 (0.65) | NT5ETAS1R3TAS1R1 | |
| Adenosine Phosphate SCHEMBL2037385 | 0.87 | P2RY1 (0.65) | NT5ETAS1R3TAS1R1 | |
| E626 SCHEMBL15670415 | 0.84 | NT5E (0.71) | HINT1NT5EIMPDH2TAS1R3TAS1R1 | |
| E626 SCHEMBL15671056 | 0.84 | NT5E (0.64) | HINT1NT5EIMPDH2TAS1R3TAS1R1 | |
| E626 SCHEMBL15670774 | 0.84 | NT5E (0.70) | HINT1NT5EIMPDH2TAS1R3TAS1R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2914131-A1 | FLAVOUR ADDITIVES | Mars, Incorporated (US) | 2015-09-09 | — | — | EP | disclosed |
| WO-2014068044-A1 | FLAVOUR ADDITIVES | MARS, INCORPORATED (US) | 2014-05-08 | — | — | WO | disclosed |