Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MITF | O75030 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | METAP2 | P50579 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.32 |
| ▸ | CCR1 | P32246 | 1/20 | 0.31 |
| ▸ | CCR5 | P51681 | 1/20 | 0.31 |
| ▸ | CCR8 | P51685 | 1/20 | 0.31 |
| ▸ | PIM1 | P11309 | 1/20 | 0.31 |
| ▸ | KIF11 | P52732 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1476570 | 0.89 | PIM1 (0.35) | KMT2AMITFALDH1A1TP53METAP2 | |
| SCHEMBL21504926 | 0.84 | CCR1 (0.50) | KMT2AHPGDTSHRALDH1A1TP53 | |
| SCHEMBL17251575 | 0.84 | KMT2A (0.37) | KMT2AMITFALDH1A1TP53METAP2 | |
| SCHEMBL15859055 | 0.80 | PIM1 (0.38) | KMT2AHPGDTSHRMEN1PIM1 | |
| SCHEMBL12210003 | 0.79 | KMT2A (0.34) | KMT2AMITFALDH1A1TP53METAP2 | |
| SCHEMBL2950568 | 0.79 | HPGD (0.45) | HPGDTSHRALDH1A1METAP2NPC1 | |
| SCHEMBL19098534 | 0.77 | NOS3 (0.43) | KMT2AALDH1A1METAP2MEN1PIM1 | |
| SCHEMBL15859021 | 0.77 | KMT2A (0.41) | KMT2AHPGDTSHRMITFALDH1A1 | |
| SCHEMBL15859023 | 0.77 | HPGD (0.38) | HPGDTSHR | |
| SCHEMBL29453375 | 0.76 | CCR1 (0.48) | KMT2AHPGDTSHRALDH1A1METAP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8722885-B1 | Phosphorescent four-coordinated platinum (II) complex | NATIONAL TSING HUA UNIVERSITY (TW) | 2014-05-13 | — | — | US | disclosed |
| US-8722885-B1 | Phosphorescent four-coordinated platinum (II) complex | NATIONAL TSING HUA UNIVERSITY (TW) | 2014-05-13 | — | — | US | disclosed |
| US-8722885-B1 | Phosphorescent four-coordinated platinum (II) complex | NATIONAL TSING HUA UNIVERSITY (TW) | 2014-05-13 | — | — | US | disclosed |
| US-20110082151-A1 | SULFONYLUREA MODULATORS OF ENDOTHELIN RECEPTOR | AUSPEX PHARMACEUTICALS, INC. (US) | 2011-04-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110082151-A1 | SULFONYLUREA MODULATORS OF ENDOTHELIN RECEPTOR | EDNRA, EDNRB, GLP1R | KMT2A 4317/4885HPGD 2985/4885TSHR 238/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.