SCHEMBL1476570

SCHEMBL1476570

CC(C)(C)c1ccnc(-c2cc(C(F)(F)F)n[nH]2)c1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PIM1 P11309 1/20 0.35
IDO1 P14902 1/20 0.35
KMT2A Q03164 2/20 0.35
MITF O75030 1/20 0.35
ALDH1A1 P00352 1/20 0.35
TP53 P04637 1/20 0.35
KIF11 P52732 1/20 0.33
NOS3 P29474 1/20 0.33
NOS2 P35228 1/20 0.33
ACHE P22303 1/20 0.33
LRRK2 Q5S007 1/20 0.32
METAP2 P50579 1/20 0.32
MEN1 O00255 1/20 0.32
NPC1 O15118 1/20 0.32
NR2F2 P24468 1/20 0.32
RAB9A P51151 1/20 0.32
KDM2B Q8NHM5 1/20 0.32
KDM5B Q9UGL1 1/20 0.32
LOXL2 Q9Y4K0 2/20 0.31
LOX P28300 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15671663 0.89 KMT2A (0.37) PIM1KMT2AMITFALDH1A1TP53
SCHEMBL19098534 0.89 NOS3 (0.43) PIM1IDO1KMT2AALDH1A1KIF11
SCHEMBL18674842 0.82 KMT2A (0.35) IDO1KMT2AMITFALDH1A1TP53
SCHEMBL2685399 0.82 CCR1 (0.48) PIM1IDO1KMT2AALDH1A1NOS3
SCHEMBL21396801 0.81 KMT2A (0.34) KMT2AMITFALDH1A1TP53MEN1
SCHEMBL17251575 0.80 KMT2A (0.37) PIM1KMT2AMITFALDH1A1TP53
SCHEMBL19083040 0.80 CYP17A1 (0.34) IDO1KMT2AMITFALDH1A1TP53
SCHEMBL17254410 0.79 NPSR1 (0.40) IDO1KMT2AMITFALDH1A1TP53
SCHEMBL15907872 0.79 IDO1 (0.37) IDO1ALDH1A1LRRK2KDM5BLOXL2
SCHEMBL12210003 0.78 KMT2A (0.34) PIM1KMT2AMITFALDH1A1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111362986-B Thieno [2,3-d ] pyridazine cyclometalated iridium complex and preparation method thereof 安徽工业大学 2023-04-07 CN disclosed
CN-111377977-B 4,7-diaryl thieno [2,3-d ] pyridazine cyclometalated iridium complex and preparation method thereof 安徽工业大学 2023-01-31 CN disclosed
CN-111377977-A 4, 7-diaryl thieno [2,3-d ] pyridazine cyclometalated iridium complex and preparation method thereof 安徽工业大学 2020-07-07 CN disclosed
CN-111362986-A Thieno [2,3-d ] pyridazine cyclometalated iridium complex and preparation method thereof 安徽工业大学 2020-07-03 CN disclosed
US-10023598-B2 Organometallic compound and organic light-emitting device including the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2018-07-17 US disclosed
US-20180155380-A1 PLATINUM COMPLEX, OLED AND APPARATUS FOR PROVIDING VISIBLE EMISSION OR NEAR-INFRARED EMISSION NATIONAL TSING HUA UNIVERSITY (TW) 2018-06-07 US disclosed
US-20170194578-A1 PLATINUM COMPLEX AND OLED USING THE SAME NATIONAL TSING HUA UNIVERSITY (TW) 2017-07-06 US disclosed
US-20170194578-A1 PLATINUM COMPLEX AND OLED USING THE SAME NATIONAL TSING HUA UNIVERSITY (TW) 2017-07-06 US disclosed
US-20160380214-A1 ORGANOMETALLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG ELECTRONICS CO LTD (KR) 2016-12-29 US disclosed
US-20160028024-A1 ORGANOMETALLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG SDI CO., LTD. (KR) 2016-01-28 US disclosed
US-8410269-B2 Phosphorescent iridium complex with non-conjugated cyclometalated ligands, synthetic method of preparing the same and phosphorescent organic light emitting diode thereof NATIONAL TSING HUA UNIVERSITY (TW) 2013-04-02 US disclosed
US-20110313161-A1 PHOSPHORESCENT IRIDIUM COMPLEX WITH NON-CONJUGATED CYCLOMETALATED LIGANDS, SYNTHETIC METHOD OF PREPARING THE SAME AND PHOSPHORESCENT ORGANIC LIGHT EMITTING DIODE THEREOF NATIONAL TSING HUA UNIVERSITY (TW) 2011-12-22 US disclosed
US-20110313161-A1 PHOSPHORESCENT IRIDIUM COMPLEX WITH NON-CONJUGATED CYCLOMETALATED LIGANDS, SYNTHETIC METHOD OF PREPARING THE SAME AND PHOSPHORESCENT ORGANIC LIGHT EMITTING DIODE THEREOF NATIONAL TSING HUA UNIVERSITY (TW) 2011-12-22 US disclosed
US-20110313162-A1 PHOSPHORESCENT IRIDIUM COMPLEX WITH NON-CONJUGATED CYCLOMETALATED LIGANDS, SYNTHETIC METHOD OF PREPARING THE SAME AND PHOSPHORESCENT ORGANIC LIGHT EMITTING DIODE THEREOF NATIONAL TSING HUA UNIVERSITY (TW) 2011-12-22 US disclosed
US-20110313162-A1 PHOSPHORESCENT IRIDIUM COMPLEX WITH NON-CONJUGATED CYCLOMETALATED LIGANDS, SYNTHETIC METHOD OF PREPARING THE SAME AND PHOSPHORESCENT ORGANIC LIGHT EMITTING DIODE THEREOF NATIONAL TSING HUA UNIVERSITY (TW) 2011-12-22 US disclosed
US-8030490-B2 Tris-chelated transition metal complex with two identical non-conjugated cyclometalated ligands; suppressing the unwanted LLCT processes, giving an enhanced emission quantum yield in the visible spectral region NATIONAL TSING HUA UNIVERSITY (TW) 2011-10-04 US disclosed
US-20110082151-A1 SULFONYLUREA MODULATORS OF ENDOTHELIN RECEPTOR AUSPEX PHARMACEUTICALS, INC. (US) 2011-04-07 US disclosed
US-7915414-B2 Blue-emitting organometallic complexes and their application Chi, Yun (TW) 2011-03-29 US disclosed
US-20080161568-A1 Phosphorescent iridium complex with non-conjugated cyclometalated ligands, synthetic method of preparing the same and phosphorescent organic light emitting diode thereof YUN CHI (TW) 2008-07-03 US disclosed
US-20080125591-A1 Blue-Emitting Organometallic Complexes And Their Application Chi, Yun (TW) 2008-05-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160380214-A1 ORGANOMETALLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME L1CAM, AP1M1, L3MBTL1 PIM1 773/4885IDO1 1035/4885KMT2A 614/4885
US-20110313161-A1 PHOSPHORESCENT IRIDIUM COMPLEX WITH NON-CONJUGATED CYCLOMETALATED LIGANDS, SYNTHETIC METHOD OF PREPARING THE SAME AND PHOSPHORESCENT ORGANIC LIGHT EMITTING DIODE THEREOF LIG3, LIG4, LIG1 PIM1 1526/4885IDO1 1778/4885KMT2A 4021/4885
US-20080161568-A1 Phosphorescent iridium complex with non-conjugated cyclometalated ligands, synthetic method of preparing the same and phosphorescent organic light emitting diode thereof LIG3, LIG4, LIG1 PIM1 1526/4885IDO1 1778/4885KMT2A 4021/4885
US-10023598-B2 Organometallic compound and organic light-emitting device including the same CRY1, LAS1L, CYBA PIM1 530/4885IDO1 395/4885KMT2A 997/4885
US-20110082151-A1 SULFONYLUREA MODULATORS OF ENDOTHELIN RECEPTOR EDNRA, EDNRB, GLP1R PIM1 1520/4885IDO1 4398/4885KMT2A 4317/4885
US-20080125591-A1 Blue-Emitting Organometallic Complexes And Their Application CYBA, IK, CRY1 PIM1 1236/4885IDO1 779/4885KMT2A 1250/4885
US-20160028024-A1 ORGANOMETALLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CHRM1, L1CAM, CHRM2 PIM1 566/4885IDO1 274/4885KMT2A 2210/4885
US-20180155380-A1 PLATINUM COMPLEX, OLED AND APPARATUS FOR PROVIDING VISIBLE EMISSION OR NEAR-INFRARED EMISSION OCIAD1, OCIAD2, CISD1 PIM1 4839/4885IDO1 430/4885KMT2A 4022/4885
US-20110313162-A1 PHOSPHORESCENT IRIDIUM COMPLEX WITH NON-CONJUGATED CYCLOMETALATED LIGANDS, SYNTHETIC METHOD OF PREPARING THE SAME AND PHOSPHORESCENT ORGANIC LIGHT EMITTING DIODE THEREOF LIG3, LIG4, LIG1 PIM1 1526/4885IDO1 1778/4885KMT2A 4021/4885
US-20170194578-A1 PLATINUM COMPLEX AND OLED USING THE SAME OCIAD2, POF1B, OCIAD1 PIM1 4716/4885IDO1 1659/4885KMT2A 3622/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.