Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.50 |
| ▸ | NFE2L2 | Q16236 | 5/20 | 0.43 |
| ▸ | KAT6A | Q92794 | 2/20 | 0.43 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.43 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | GBA1 | P04062 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.40 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.40 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.40 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.40 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.40 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31560093 | 1.00 | ELANE (0.50) | ELANENFE2L2KAT6AAKR1B1KCNA5 | |
| SCHEMBL10381875 | 0.83 | ELANE (0.58) | ELANEKMT2AALDH1A1TDP1 | |
| SCHEMBL29985855 | 0.83 | ELANE (0.58) | ELANEKMT2AALDH1A1TDP1 | |
| SCHEMBL250919 | 0.81 | AKR1B1 (0.53) | NFE2L2KAT6AAKR1B1KCNA5KMT2A | |
| SCHEMBL2124755 | 0.81 | AKR1B1 (0.53) | NFE2L2KAT6AAKR1B1KCNA5KMT2A | |
| SCHEMBL29965315 | 0.81 | NFE2L2 (0.44) | NFE2L2KAT6AAKR1B1KCNA5KMT2A | |
| SCHEMBL30333632 | 0.81 | AKR1B1 (0.53) | NFE2L2KAT6AAKR1B1KCNA5KMT2A | |
| SCHEMBL547735 | 0.81 | NFE2L2 (0.44) | NFE2L2KAT6AAKR1B1KCNA5KMT2A | |
| SCHEMBL29141546 | 0.80 | PTGES2 (0.47) | ELANENFE2L2KAT6AAKR1B1KCNA5 | |
| SCHEMBL2051439 | 0.79 | NFE2L2 (0.43) | NFE2L2KAT6AAKR1B1KCNA5KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111370766-A | Electrolyte containing-S-F group compound and electrochemical device thereof | 青岛滨海学院 | 2020-07-03 | — | — | CN | claimed |
| CN-102131792-B | Process for preparation of apoptosis promoter ABT-263 | ABBOTT LAB | 2014-05-07 | — | — | CN | claimed |
| EP-2307393-B1 | A PROCESS FOR THE PREPARATION OF THE APOPTOSIS PROMOTER ABT-263 | ABBOTT LAB (US) | 2013-04-10 | — | — | EP | claimed |
| US-8168784-B2 | Processes to make apoptosis promoters | ABBOTT LABORATORIES (US) | 2012-05-01 | — | — | US | claimed |
| JP-2011525182-A | — | — | 2011-09-15 | — | — | JP | claimed |
| CN-102131792-A | Process for preparation of apoptosis promoter abt-263 | ABBOTT LAB | 2011-07-20 | — | — | CN | claimed |
| EP-2307393-A1 | A PROCESS FOR THE PREPARATION OF THE APOPTOSIS PROMOTER ABT-263 | Abbott Laboratories (US) | 2011-04-13 | — | — | EP | claimed |
| US-20090318689-A1 | Processes To Make Apoptosis Promoters | ABBOTT LABORATORIES (US) | 2009-12-24 | — | — | US | claimed |
| WO-2009155386-A1 | A PROCESS FOR THE PREPARATION OF THE APOPTOSIS PROMOTER ABT-263 | ABBOTT LABORATORIES (US) | 2009-12-23 | — | — | WO | claimed |
| JP-2008524166-A | — | — | 2008-07-10 | — | — | JP | claimed |
| EP-1833805-A1 | NEW 3-PHENYLPROPIONIC ACID DERIVATIVES FOR THE TREATMENT OF DIABETES | Adamed SP. Z O.O. (PL) | 2007-09-19 | — | — | EP | claimed |
| WO-2006067086-A1 | NEW 3-PHENYLPROPIONIC ACID DERIVATIVES FOR THE TREATMENT OF DIABETES | ADAMED SP. Z O.O. (PL) | 2006-06-29 | — | — | WO | claimed |
| US-4369145-A | Preparation of fluorobenzenesulfonyl fluorides by exchange fluorination | RHONE-POULENC INDUSTRIES (FR) | 1983-01-18 | — | — | US | claimed |
| CN-117279889-A | Substituted fluorosulfates and uses thereof | 深圳湾实验室 | 2023-12-22 | — | — | CN | disclosed |
| CN-111370766-A | Electrolyte containing-S-F group compound and electrochemical device thereof | 青岛滨海学院 | 2020-07-03 | — | — | CN | disclosed |
| CN-109851535-A | A method of preparing 4- fluoro- 3- (trifyl) benzsulfamide | 天津现代职业技术学院 | 2019-06-07 | — | — | CN | disclosed |
| US-4886629-A | Process for the preparation of fluorinated benzene sulfonyl fluorides | ALLIED-SIGNAL INC. (US) | 1989-12-12 | — | — | US | disclosed |
| EP-0032077-B1 | PROCESS FOR PREPARING FLUOROBENZENE-SULFONYL FLUORIDES | RHONE-POULENC SPECIALITES CHIMIQUES (FR) | 1983-06-22 | — | — | EP | disclosed |
| US-4369145-A | Preparation of fluorobenzenesulfonyl fluorides by exchange fluorination | RHONE-POULENC INDUSTRIES (FR) | 1983-01-18 | — | — | US | disclosed |
| EP-0032077-A1 | Process for preparing fluorobenzene-sulfonyl fluorides | RHONE-POULENC SPECIALITES CHIMIQUES (FR) | 1981-07-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090318689-A1 | Processes To Make Apoptosis Promoters | BAX, BCL2, CCAR2 | ELANE 2233/4885NFE2L2 356/4885KAT6A 616/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.