Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 1/20 | 0.53 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | CNR2 | P34972 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | HTR2C | P28335 | 1/20 | 0.47 |
| ▸ | HTR2B | P41595 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 2/20 | 0.46 |
| ▸ | CNR1 | P21554 | 2/20 | 0.45 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.44 |
| ▸ | KAT6A | Q92794 | 2/20 | 0.44 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL250919 | 1.00 | AKR1B1 (0.53) | AKR1B1HSD11B1GAAKMT2ACNR2 | |
| SCHEMBL30333632 | 1.00 | AKR1B1 (0.53) | AKR1B1HSD11B1GAAKMT2ACNR2 | |
| SCHEMBL4615886 | 0.87 | CNR2 (0.45) | AKR1B1HSD11B1GAAKMT2ACNR2 | |
| SCHEMBL776706 | 0.85 | HTR6 (0.57) | AKR1B1HSD11B1GAAKMT2ACNR2 | |
| SCHEMBL7832587 | 0.85 | AKR1B1 (0.44) | AKR1B1HSD11B1GAAKMT2ACNR2 | |
| SCHEMBL29965315 | 0.83 | NFE2L2 (0.44) | AKR1B1HSD11B1KMT2ANFE2L2KAT6A | |
| SCHEMBL547735 | 0.83 | NFE2L2 (0.44) | AKR1B1HSD11B1KMT2ANFE2L2KAT6A | |
| SCHEMBL16494982 | 0.83 | HTR2A (0.48) | AKR1B1HSD11B1KMT2ACNR2MEN1 | |
| SCHEMBL13343182 | 0.83 | CNR1 (0.58) | CNR2CNR1 | |
| SCHEMBL6502551 | 0.83 | AKR1B1 (0.42) | AKR1B1HSD11B1GAAKMT2ACNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2443172-B1 | AROMATIC POLYETHERSULFONE BLOCK COPOLYMERS | BASF SE (DE) | 2016-09-21 | — | — | EP | disclosed |
| EP-2443172-A1 | AROMATIC POLYETHERSULFONE BLOCK COPOLYMERS | BASF SE (DE) | 2012-04-25 | — | — | EP | disclosed |
| WO-2010146052-A1 | AROMATIC POLYETHERSULFONE BLOCK COPOLYMERS | BASF SE (DE) | 2010-12-23 | — | — | WO | disclosed |