Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | COMT | P21964 | 3/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15680165 | 0.82 | TYR (0.33) | TYRCOMT | |
| SCHEMBL19425992 | 0.78 | ALDH1A1 (0.38) | TYRBCHEMAPTCOMT | |
| SCHEMBL13467618 | 0.75 | TYR (0.42) | TYRCOMT | |
| SCHEMBL15680168 | 0.73 | TYR (0.32) | TYR | |
| SCHEMBL12968429 | 0.72 | TYR (0.38) | TYRCOMT | |
| SCHEMBL15680210 | 0.71 | TYR (0.35) | TYRCOMTBRD4 | |
| SCHEMBL9664988 | 0.70 | COMT (0.40) | TYRCOMT | |
| SCHEMBL15632351 | 0.70 | TYR (0.36) | TYR | |
| SCHEMBL19425993 | 0.70 | MAPT (0.34) | TYRBCHEMAPTCOMT | |
| SCHEMBL9357301 | 0.69 | TYR (0.34) | TYRCOMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014068388-A1 | 2 SUBSTITUTED CEPHEM COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2014-05-08 | — | — | WO | disclosed |