Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NNMT | P40261 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 4/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | SLC9A1 | P19634 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15698695 | 0.82 | ALDH1A1 (0.40) | SMN1; SMN2KMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL15711614 | 0.81 | KDM4E (0.40) | ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL15698617 | 0.79 | POLB (0.33) | POLBL3MBTL1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL8587349 | 0.72 | POLB (0.39) | POLBL3MBTL1KMT2AMEN1SLC9A1 | |
| SCHEMBL15711606 | 0.67 | ALDH1A1 (0.39) | POLBL3MBTL1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL15698543 | 0.66 | CELA1 (0.37) | POLBL3MBTL1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL353258 | 0.66 | MEN1 (0.49) | POLBL3MBTL1KMT2AMEN1SLC9A1 | |
| SCHEMBL10547456 | 0.63 | GSK3B (0.35) | POLBL3MBTL1KMT2AMEN1SLC9A1 | |
| SCHEMBL6800447 | 0.60 | CYP3A4 (0.50) | POLBSMN1; SMN2KMT2AMEN1ALDH1A1 | |
| SCHEMBL4522155 | 0.60 | SLC9A1 (0.40) | POLBL3MBTL1SMN1; SMN2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8729110-B1 | 2-thio-1,3,4-oxadiazoles derivatives as sphingosine-1 phosphate receptors modulators | ALLERGAN, INC. (US) | 2014-05-20 | — | — | US | disclosed |