Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 17/20 | 0.52 |
| ▸ | SCD | O00767 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | RBP4 | P02753 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15689502 | 0.85 | GPR119 (0.55) | GPR119SCDCYP2C9CYP2C19 | |
| SCHEMBL15689500 | 0.85 | GPR119 (0.55) | GPR119SCDCYP2C9CYP2C19 | |
| SCHEMBL15689498 | 0.82 | GPR119 (0.54) | GPR119SCDRBP4 | |
| SCHEMBL15689497 | 0.82 | GPR119 (0.54) | GPR119SCDRBP4 | |
| SCHEMBL15699581 | 0.82 | GPR119 (0.54) | GPR119SCDRBP4 | |
| SCHEMBL15699583 | 0.82 | GPR119 (0.54) | GPR119SCDRBP4 | |
| SCHEMBL14157572 | 0.81 | GPR119 (0.55) | GPR119CYP2C9CYP2C19 | |
| SCHEMBL14157573 | 0.81 | GPR119 (0.55) | GPR119CYP2C9CYP2C19 | |
| SCHEMBL14239293 | 0.77 | GPR119 (0.51) | GPR119CYP2C9CYP2C19 | |
| SCHEMBL26506522 | 0.75 | SCD (0.41) | SCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014074668-A1 | MODULATORS OF GPR119 AND THE TREATMENT OF DISORDERS RELATED THERETO | ARENA PHARMACEUTICALS, INC. (US) | 2014-05-15 | — | — | WO | disclosed |