SCHEMBL157010

SCHEMBL157010

O=S(=O)(O)CC(O)CNC1CCCCC1

nearest known ligand 0.66

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.66
SMN1; SMN2 Q16637 2/20 0.53
HTT P42858 2/20 0.53
ANPEP P15144 2/20 0.45
ERAP2 Q6P179 2/20 0.45
SLC2A1 P11166 1/20 0.42
KMT2A Q03164 4/20 0.38
MEN1 O00255 3/20 0.38
LMNA P02545 2/20 0.38
POLB P06746 1/20 0.37
ALDH1A1 P00352 1/20 0.37
MAPT P10636 1/20 0.37
ADRB2 P07550 1/20 0.37
CA12 O43570 1/20 0.36
CA1 P00915 1/20 0.36
CA7 P43166 1/20 0.36
CA14 Q9ULX7 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5447671 1.00 KDM4E (0.66) KDM4ESMN1; SMN2HTTANPEPERAP2
SCHEMBL2142228 1.00 KDM4E (0.66) KDM4ESMN1; SMN2HTTANPEPERAP2
SCHEMBL30287648 0.98 KDM4E (0.63) KDM4ESMN1; SMN2HTTANPEPERAP2
SCHEMBL1442829 0.98 KDM4E (0.63) KDM4ESMN1; SMN2HTTANPEPERAP2
Bicarbonate SCHEMBL23462324 0.95 KDM4E (0.59) KDM4ESMN1; SMN2HTTANPEPERAP2
Hexamethonium SCHEMBL8821557 0.86 KDM4E (0.49) KDM4ESMN1; SMN2HTTANPEPERAP2
SCHEMBL18577849 0.84 KDM4E (0.46) KDM4ESMN1; SMN2HTTANPEPERAP2
SCHEMBL29710685 0.83 KDM4E (0.61) KDM4ESMN1; SMN2HTTANPEPERAP2
Potassium Ion SCHEMBL30898940 0.83 KDM4E (0.61) KDM4ESMN1; SMN2HTTANPEPERAP2
SCHEMBL13359411 0.83 KDM4E (0.43) KDM4ESMN1; SMN2HTTKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 6802 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3986465-B1 SITE-SPECIFIC, KINETICALLY INERT CONJUGATION OF LABELS AND/OR CARRIERS TO TARGET MOLECULES SUCH AS HIS-TAGGED PROTEINS VIA METAL COMPLEX REAGENTS MAX PLANCK GESELLSCHAFT (DE) 2026-05-13 EP claimed
EP-4739992-A1 DETECTION OF TARGET MOLECULES IN DRIED BIOLOGIC MATRICES SomaLogic Operating Co., Inc. (US) 2026-05-13 EP claimed
EP-4735620-A1 METHODS AND FORMULATIONS FOR DENATURING DNA Illumina, Inc. (US) 2026-05-06 EP claimed
WO-2026085618-A1 METHOD OF IMMOBILIZING CAPTURE PROBES TO SOLID PHASES FOR TARGET SUBSTANCE DETECTION YYZ PHARMATECH INC. (CA) 2026-04-30 WO claimed
EP-4727953-A2 ACCELERATED MARKING OF 5-FORMYL CYTOSINE AND USE IN NUCLEIC ACID METHYLATION SEQUENCING F. Hoffmann-La Roche AG (CH) 2026-04-22 EP claimed
EP-4724588-A1 A METHOD OF ENHANCED SEPARATION OF FULL ADENO-ASSOCIATED VIRUS (AAV) CAPSIDS Sartorius BIA Separations d.o.o. (SI) 2026-04-15 EP claimed
US-12582670-B2 Lignin solvation using aqueous biologically compatible buffers UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) 2026-03-24 US claimed
EP-4684030-A2 METHOD OF DEPROTECTING AT LEAST ONE D-AMINO ACID AND/OR D-AMINO ACID DERIVATIVE PROTECTED FUNCTIONAL GROUP Martin-Luther-Universität Halle-Wittenberg (DE) 2026-01-28 EP claimed
WO-2025262036-A1 METHOD OF MANUFACTURING A PHARMACEUTICAL COMPOSITION RNASSIST LTD (GB) 2025-12-26 WO claimed
EP-4665300-A1 METHODS AND COMPOSITIONS FOR FORMULATING RECOMBINANT VIRAL VECTORS President and Fellows of Harvard College (US) 2025-12-24 EP claimed
US-5410026-A Method for refolding insoluble, misfolded insulin-like growth factor-1 into an active conformation GENENTECH, INC. (US) 1995-04-25 US claimed
WO-1995006064-A1 REFOLDING OF POLYPEPTIDES LIKE RECOMBINANT INSULIN-LIKE GROWTH FACTOR IGF-I GENENTECH, INC. (US) 1995-03-02 WO claimed
EP-0618971-A1 METHOD FOR REFOLDING IGF-I TO ACTIVE CONFORMATION GENENTECH, INC. (US) 1994-10-12 EP claimed
EP-0363108-B1 Wash solution containing a cationic surfactant and its use in chlamydial and gonococcal determinations EASTMAN KODAK CO (US) 1994-07-13 EP claimed
US-5288931-A Incubating isolated growth factor in alkaline buffer with low concentrations of chaotropic and reducing agents GENENTECH, INC. (US) 1994-02-22 US claimed
US-5234817-A Wash solution containing a cationic surfactant and its use in chlamydial and gonococcal determinations EASTMAN KODAK COMPANY (US) 1993-08-10 US claimed
WO-1993011240-A1 METHOD FOR REFOLDING IGF-I TO ACTIVE CONFORMATION GENENTECH, INC. (US) 1993-06-10 WO claimed
EP-0203334-B1 MEANS AND METHOD FOR THE DETERMINATION OF CALCIUM MERCK PATENT GmbH (DE) 1990-01-03 EP claimed
US-4871678-A O-CRESOLPHTHALEIN COMPLEXONE, ACID, SULFONIC ACID AMINE ZWITTERIONIC BUFFER BESCHRANKTER HAFTUNG (DE) 1989-10-03 US claimed
EP-0203334-A2 Means and method for the determination of calcium MERCK PATENT GmbH (DE) 1986-12-03 EP claimed