Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | ANPEP | P15144 | 2/20 | 0.42 |
| ▸ | ERAP2 | Q6P179 | 2/20 | 0.42 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29710685 | 0.97 | KDM4E (0.61) | KDM4ESMN1; SMN2HTTANPEPERAP2 | |
| SCHEMBL157010 | 0.83 | KDM4E (0.66) | KDM4ESMN1; SMN2HTTANPEPERAP2 | |
| SCHEMBL5447671 | 0.83 | KDM4E (0.66) | KDM4ESMN1; SMN2HTTANPEPERAP2 | |
| SCHEMBL2142228 | 0.83 | KDM4E (0.66) | KDM4ESMN1; SMN2HTTANPEPERAP2 | |
| SCHEMBL30287648 | 0.81 | KDM4E (0.63) | KDM4ESMN1; SMN2HTTANPEPERAP2 | |
| SCHEMBL1442829 | 0.81 | KDM4E (0.63) | KDM4ESMN1; SMN2HTTANPEPERAP2 | |
| Bicarbonate SCHEMBL23462324 | 0.79 | KDM4E (0.59) | KDM4ESMN1; SMN2HTTANPEPERAP2 | |
| SCHEMBL27980382 | 0.78 | KDM4E (1.00) | KDM4ESMN1; SMN2HTTANPEPERAP2 | |
| SCHEMBL25239362 | 0.73 | KDM4E (0.40) | KDM4ESMN1; SMN2HTTANPEPERAP2 | |
| SCHEMBL3535515 | 0.72 | KDM4E (0.79) | KDM4ESMN1; SMN2HTTANPEPERAP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118056912-A | Regeneration reagent, kit containing same and application of regeneration reagent | 深圳华大智造科技股份有限公司 | 2024-05-21 | — | — | CN | claimed |
| CN-118056912-A | Regeneration reagent, kit containing same and application of regeneration reagent | 深圳华大智造科技股份有限公司 | 2024-05-21 | — | — | CN | disclosed |