Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 1/20 | 0.55 |
| ▸ | DCLK1 | O15075 | 1/20 | 0.49 |
| ▸ | FES | P07332 | 1/20 | 0.49 |
| ▸ | PIM1 | P11309 | 1/20 | 0.49 |
| ▸ | CDK2 | P24941 | 1/20 | 0.49 |
| ▸ | GSK3A | P49840 | 1/20 | 0.49 |
| ▸ | GSK3B | P49841 | 1/20 | 0.49 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.49 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.49 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.49 |
| ▸ | HIPK4 | Q8NE63 | 1/20 | 0.49 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.49 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.49 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.49 |
| ▸ | MAP4K5 | Q9Y4K4 | 1/20 | 0.49 |
| ▸ | CSNK1G3 | Q9Y6M4 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17148443 | 0.97 | NTRK1 (0.53) | NTRK1DCLK1FESPIM1CDK2 | |
| SCHEMBL15701126 | 0.89 | NTRK1 (0.45) | NTRK1DCLK1FESPIM1CDK2 | |
| SCHEMBL15701165 | 0.83 | ACP1 (0.46) | NTRK1KDM4ECASP3SENP7SENP8 | |
| SCHEMBL15701281 | 0.80 | MAPT (0.64) | NTRK1KDM4ENPSR1RXFP1NPC1 | |
| SCHEMBL15701028 | 0.80 | RAB9A (0.48) | NTRK1KDM4ECASP3SENP7SENP8 | |
| SCHEMBL15701026 | 0.80 | RAB9A (0.48) | NTRK1KDM4ECASP3SENP7SENP8 | |
| SCHEMBL15701139 | 0.78 | DYRK1A (0.42) | NTRK1KDM4ECASP3SENP7SENP8 | |
| SCHEMBL15701057 | 0.78 | CASP3 (0.45) | NTRK1KDM4ENPSR1CASP3SENP7 | |
| SCHEMBL19446717 | 0.78 | RAB9A (0.52) | KDM4ERXFP1CASP3SENP7SENP8 | |
| SCHEMBL15701278 | 0.77 | CASP3 (0.50) | KDM4ECASP3SENP7SENP8SENP6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2914592-B1 | INHIBITORS OF CYTOMEGALOVIRUS | BOEHRINGER INGELHEIM INT (DE) | 2017-10-11 | — | — | EP | disclosed |
| WO-2014070979-A1 | INHIBITORS OF CYTOMEGALOVIRUS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2014-05-08 | — | — | WO | disclosed |