Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 3/20 | 0.46 |
| ▸ | P2RY1 | P47900 | 8/20 | 0.46 |
| ▸ | P2RY2 | P41231 | 2/20 | 0.46 |
| ▸ | GPR17 | Q13304 | 2/20 | 0.44 |
| ▸ | P2RY11 | Q96G91 | 3/20 | 0.43 |
| ▸ | ENPP1 | P22413 | 2/20 | 0.42 |
| ▸ | P2RX1 | P51575 | 2/20 | 0.42 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.42 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.42 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.41 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15713278 | 0.91 | NT5E (0.49) | NT5EP2RY1P2RY11LMNATP53 | |
| SCHEMBL22508597 | 0.90 | P2RY1 (0.58) | NT5EP2RY1P2RY2GPR17P2RY11 | |
| SCHEMBL13604126 | 0.88 | P2RX3 (0.49) | P2RY1P2RY2GPR17P2RX1P2RX3 | |
| SCHEMBL6264026 | 0.85 | P2RX3 (0.43) | P2RY1GPR17P2RY11ENPP1P2RX1 | |
| SCHEMBL17117775 | 0.84 | NT5E (0.64) | NT5EP2RY1P2RY2GPR17P2RY11 | |
| SCHEMBL25581750 | 0.84 | NT5E (0.53) | NT5EP2RY1P2RY2P2RY11ENPP1 | |
| SCHEMBL12932285 | 0.83 | P2RY1 (0.52) | NT5EP2RY1P2RY2GPR17P2RY11 | |
| SCHEMBL1064322 | 0.83 | P2RY1 (0.52) | NT5EP2RY1P2RY2GPR17P2RY11 | |
| SCHEMBL9601455 | 0.82 | NT5E (0.61) | NT5EP2RY1P2RY2P2RY11LMNA | |
| SCHEMBL24825639 | 0.81 | CA5A (0.54) | NT5EP2RY1P2RY2GPR17P2RY11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2917341-B1 | NEW PHOSPHODEOXYRIBOSYLTRANSFERASE MUTANT ENZYMES AND USES THEREOF | CENTRE NAT DE LA RECH SCIENT (C N R S ) (FR) | 2017-09-27 | — | — | EP | disclosed |
| WO-2014072487-A1 | NEW PHOSPHODEOXYRIBOSYLTRANSFERASE MUTANT ENZYMES AND USES THEREOF | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2014-05-15 | — | — | WO | disclosed |