SCHEMBL15714293

SCHEMBL15714293

COC(=O)c1oc2ccc(C(F)(F)F)cc2c1NS(C)(=O)=O

nearest known ligand 0.48

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 4/20 0.48
KDM4E B2RXH2 5/20 0.46
MAPK1 P28482 1/20 0.46
ALDH1A1 P00352 3/20 0.45
HPGD P15428 3/20 0.45
HSD17B10 Q99714 2/20 0.45
TSHR P16473 2/20 0.45
MEN1 O00255 1/20 0.45
KMT2A Q03164 1/20 0.45
CFTR P13569 1/20 0.41
KIF11 P52732 1/20 0.41
SMN1; SMN2 Q16637 4/20 0.41
TP53 P04637 3/20 0.41
HTT P42858 1/20 0.41
EPHX2 P34913 1/20 0.39
NR1H4 Q96RI1 1/20 0.39
MAPT P10636 2/20 0.38
POLB P06746 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17179770 0.86 HIF1A (0.54) HIF1AKDM4EMAPK1ALDH1A1HPGD
SCHEMBL15714338 0.83 KDM4E (0.67) KDM4EMAPK1ALDH1A1HPGDHSD17B10
SCHEMBL17179768 0.82 KDM4E (0.53) HIF1AKDM4EMAPK1ALDH1A1HPGD
SCHEMBL30554652 0.80 CFTR (0.47) HIF1AKDM4EMAPK1ALDH1A1HPGD
SCHEMBL17179764 0.80 CFTR (0.47) HIF1AKDM4EMAPK1ALDH1A1HPGD
SCHEMBL15714295 0.80 CFTR (0.47) HIF1AKDM4EMAPK1ALDH1A1HPGD
SCHEMBL15714086 0.80 HIF1A (0.58) HIF1AKDM4EALDH1A1HPGDHSD17B10
SCHEMBL17179769 0.79 HPGD (0.72) KDM4EMAPK1ALDH1A1HPGDHSD17B10
SCHEMBL17179762 0.79 KDM4E (0.65) HIF1AKDM4EMAPK1ALDH1A1HPGD
SCHEMBL15714263 0.78 KDM4E (0.58) KDM4EMAPK1ALDH1A1HPGDHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150289512-A1 METHOD FOR PROMOTING PLANT GROWTH SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-10-15 US disclosed
US-20150289512-A1 METHOD FOR PROMOTING PLANT GROWTH SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-10-15 US disclosed
WO-2014073627-A1 METHOD FOR PROMOTING PLANT GROWTH 住友化学株式会社 (JP) 2014-05-15 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150289512-A1 METHOD FOR PROMOTING PLANT GROWTH FGF1, MKI67, FGF2 HIF1A 118/4885KDM4E 2837/4885MAPK1 94/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.