SCHEMBL15714263

SCHEMBL15714263

COC(=O)c1oc2ccccc2c1NS(C)(=O)=O

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 9/20 0.58
SMN1; SMN2 Q16637 3/20 0.57
ALDH1A1 P00352 5/20 0.56
LMNA P02545 2/20 0.56
NPSR1 Q6W5P4 2/20 0.47
MAPT P10636 2/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
TSHR P16473 5/20 0.46
HSD17B10 Q99714 4/20 0.46
HPGD P15428 3/20 0.46
MEN1 O00255 1/20 0.45
KMT2A Q03164 1/20 0.45
CYP1A2 P05177 2/20 0.45
CYP3A4 P08684 2/20 0.45
CYP2C9 P11712 2/20 0.45
USP2 O75604 1/20 0.45
CYP2D6 P10635 1/20 0.45
CYP2C19 P33261 1/20 0.45
ALOX15 P16050 1/20 0.44
MAPK1 P28482 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15714264 0.86 SMN1; SMN2 (0.58) KDM4ESMN1; SMN2ALDH1A1LMNATSHR
SCHEMBL16396579 0.84 ALDH1A1 (0.58) KDM4EALDH1A1LMNANPSR1MAPT
SCHEMBL16905806 0.82 KDM4E (0.65) KDM4ESMN1; SMN2ALDH1A1LMNANPSR1
SCHEMBL15714287 0.79 TSHR (0.68) KDM4ESMN1; SMN2ALDH1A1LMNANPSR1
SCHEMBL17179775 0.78 SMN1; SMN2 (0.62) KDM4ESMN1; SMN2ALDH1A1LMNANPSR1
SCHEMBL16902654 0.78 SMN1; SMN2 (0.66) KDM4ESMN1; SMN2ALDH1A1LMNANPSR1
SCHEMBL15714293 0.78 HIF1A (0.48) KDM4ESMN1; SMN2ALDH1A1MAPTTSHR
SCHEMBL2392417 0.76 SMN1; SMN2 (0.63) KDM4ESMN1; SMN2ALDH1A1LMNANPSR1
SCHEMBL15714138 0.76 TSHR (0.73) KDM4ESMN1; SMN2ALDH1A1LMNANPSR1
SCHEMBL23461860 0.75 KDM4E (0.69) KDM4ESMN1; SMN2ALDH1A1LMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150289512-A1 METHOD FOR PROMOTING PLANT GROWTH SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-10-15 US disclosed
US-20150289512-A1 METHOD FOR PROMOTING PLANT GROWTH SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-10-15 US disclosed
WO-2014073627-A1 METHOD FOR PROMOTING PLANT GROWTH 住友化学株式会社 (JP) 2014-05-15 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150289512-A1 METHOD FOR PROMOTING PLANT GROWTH FGF1, MKI67, FGF2 KDM4E 2837/4885SMN1; SMN2 4564/4885ALDH1A1 653/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.