Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD274 | Q9NZQ7 | 5/20 | 0.43 |
| ▸ | BCHE | P06276 | 3/20 | 0.43 |
| ▸ | CNR2 | P34972 | 3/20 | 0.43 |
| ▸ | CA12 | O43570 | 5/20 | 0.43 |
| ▸ | CA1 | P00915 | 5/20 | 0.43 |
| ▸ | CA2 | P00918 | 5/20 | 0.43 |
| ▸ | CA9 | Q16790 | 5/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.39 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15258425 | 0.95 | CD274 (0.44) | CD274BCHECNR2CA12CA1 | |
| SCHEMBL12222536 | 0.92 | CD274 (0.44) | CD274BCHECNR2CA12CA1 | |
| SCHEMBL16342025 | 0.91 | CD274 (0.47) | CD274BCHECNR2CA12CA1 | |
| SCHEMBL14586325 | 0.88 | CD274 (0.43) | CD274BCHECNR2CA12CA1 | |
| SCHEMBL14511687 | 0.85 | ADRB2 (0.40) | CD274BCHECNR2CA12CA1 | |
| SCHEMBL13857331 | 0.81 | TAS1R3 (0.45) | CD274BCHECNR2CA12CA1 | |
| SCHEMBL12706029 | 0.77 | TP53 (0.42) | BCHECNR2CA12CA1CA2 | |
| SCHEMBL17169750 | 0.76 | TDP1 (0.51) | BCHECNR2CA12CA1CA2 | |
| SCHEMBL20193876 | 0.76 | TDP1 (0.51) | BCHECNR2CA12CA1CA2 | |
| SCHEMBL13752387 | 0.74 | TDP1 (0.53) | CA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8729030-B2 | Peptides that bind to the erythropoietin receptor | AFFYMAX, INC. (US) | 2014-05-20 | — | — | US | disclosed |