Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP1 | P53582 | 4/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | ACHE | P22303 | 6/20 | 0.49 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 2/20 | 0.41 |
| ▸ | DRD2 | P14416 | 2/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | HTR7 | P34969 | 1/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4525381 | 0.85 | METAP1 (0.49) | METAP1TSHRACHECHRNA7ALDH1A1 | |
| SCHEMBL29608349 | 0.83 | POLB (0.48) | METAP1ACHEALDH1A1TDP1 | |
| SCHEMBL7620135 | 0.80 | METAP1 (0.47) | METAP1ACHECHRNA7 | |
| SCHEMBL7623809 | 0.78 | CHRNA7 (0.46) | METAP1ACHECHRNA7 | |
| SCHEMBL10427066 | 0.75 | ACHE (0.52) | METAP1TSHRACHEALDH1A1TDP1 | |
| SCHEMBL28793895 | 0.75 | ACHE (0.52) | METAP1TSHRACHEALDH1A1TDP1 | |
| SCHEMBL31727672 | 0.75 | ACHE (0.52) | METAP1TSHRACHEKDM4EHTR1A | |
| SCHEMBL18825273 | 0.74 | ACHE (0.50) | METAP1ACHEHTR1ADRD2HTR2A | |
| SCHEMBL11034800 | 0.74 | TSHR (0.47) | METAP1TSHRCHRNA7ALDH1A1TDP1 | |
| SCHEMBL5471012 | 0.72 | METAP1 (1.00) | METAP1ACHEHTR1ADRD2HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014076965-A1 | 1-INDANE DERIVATIVE HAVING ANTI-PROTOZOAL ACTIVITY | 学校法人北里研究所 (JP) | 2014-05-22 | — | — | WO | disclosed |