Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.44 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | APOBEC3A | P31941 | 2/20 | 0.38 |
| ▸ | APOBEC3G | Q9HC16 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RXRA | P19793 | 1/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenol SCHEMBL16011615 | 0.84 | ESR1 (0.45) | PPARGLMNACTDSP1KDM4ESMN1; SMN2 | |
| SCHEMBL2690874 | 0.83 | MAPT (0.48) | LMNAHSD17B10KDM4ESMN1; SMN2NPC1 | |
| SCHEMBL21577923 | 0.79 | HSD17B10 (0.55) | CYP4A11CYP4F2HSD17B10NR1H4SMN1; SMN2 | |
| SCHEMBL1743772 | 0.78 | MAPT (0.54) | CYP4A11CYP4F2HSD17B10NR1H4SMN1; SMN2 | |
| SCHEMBL3790673 | 0.77 | NR1H4 (0.51) | LMNAHSD17B10NR1H4FFAR1RXRA | |
| SCHEMBL7855043 | 0.77 | CYP4A11 (0.68) | CYP4A11CYP4F2HSD17B10RXRANR1H2 | |
| SCHEMBL8997287 | 0.77 | CYP4A11 (0.54) | CYP4A11CYP4F2RXRANR1H2CA12 | |
| SCHEMBL8465670 | 0.77 | LMNA (0.64) | LMNACTDSP1KDM4ESMN1; SMN2FFAR1 | |
| SCHEMBL8293510 | 0.76 | RARB (0.55) | CYP4A11CYP4F2ALDH1A1MAPT | |
| SCHEMBL1560634 | 0.76 | CYP4A11 (0.69) | CYP4A11CYP4F2NR1H2CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2920142-A1 | METHANOFULLERENES | Robinson, Alex Philip, Graham (GB) | 2015-09-23 | — | — | EP | disclosed |
| WO-2014190070-A1 | FULLERENES | ROBINSON ALEX PHILIP GRAAHAM (US) | 2014-11-27 | — | — | WO | disclosed |
| WO-2014137663-A1 | METHANOFULLERENES | ROBINSON ALEX PHILIP GRAHAM (GB) | 2014-09-12 | — | — | WO | disclosed |
| WO-2014078097-A1 | METHANOFULLERENES | ROBINSON ALEX PHILIP GRAHAM (GB) | 2014-05-22 | — | — | WO | disclosed |