Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | SYK | P43405 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20954296 | 0.88 | KMT2A (0.46) | MAPTRAB9AKMT2AMEN1ALDH1A1 | |
| SCHEMBL15716142 | 0.83 | CYP4A11 (0.44) | MAPTRAB9AALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL24848155 | 0.80 | KMT2A (0.69) | MAPTRAB9AKMT2AMEN1ALDH1A1 | |
| SCHEMBL28946325 | 0.80 | ALDH1A1 (0.51) | MAPTRAB9AKMT2AMEN1ALDH1A1 | |
| SCHEMBL9099162 | 0.80 | CYP17A1 (0.52) | MAPTRAB9AKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL21360453 | 0.79 | KMT2A (0.57) | MAPTRAB9AKMT2AMEN1ALDH1A1 | |
| SCHEMBL4562895 | 0.79 | ELANE (0.49) | MAPTRAB9AKMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL21557047 | 0.78 | CA1 (0.47) | MAPTRAB9AKMT2AMEN1ALDH1A1 | |
| SCHEMBL1000794 | 0.78 | NR1H4 (0.49) | ALDH1A1GAAHPGDTSHRHSD17B10 | |
| SCHEMBL8983815 | 0.77 | KMT2A (0.50) | MAPTRAB9AKMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8168821-B2 | Cyclopropylacetic acid derivatives and use thereof | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2012-05-01 | — | — | US | disclosed |
| US-20090286882-A1 | Cyclopropylacetic Acid Derivatives and Use Thereof | BAYER HEALTHCARE AG (DE) | 2009-11-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090286882-A1 | Cyclopropylacetic Acid Derivatives and Use Thereof | PCCA, PPP2CA, HMGCR | MAPT 3539/4885RAB9A 3140/4885KMT2A 4509/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.