Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS12 | P56730 | 14/20 | 0.74 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.54 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.54 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.54 |
| ▸ | MPL | P40238 | 2/20 | 0.52 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.52 |
| ▸ | RHEB | Q15382 | 1/20 | 0.48 |
| ▸ | F2 | P00734 | 1/20 | 0.48 |
| ▸ | F10 | P00742 | 1/20 | 0.48 |
| ▸ | PLG | P00747 | 1/20 | 0.48 |
| ▸ | PLAT | P00750 | 1/20 | 0.48 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.48 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2714153 | 0.87 | PRSS12 (0.75) | PRSS12NR2E3RHEBF2F10 | |
| SCHEMBL15716913 | 0.79 | PRSS12 (0.63) | PRSS12NR2E3F2F10PLG | |
| SCHEMBL1248994 | 0.76 | DGAT1 (0.73) | PRSS12HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL10244014 | 0.76 | PRSS12 (0.68) | PRSS12NR2E3RHEBF2F10 | |
| SCHEMBL10243990 | 0.73 | PRSS12 (0.72) | PRSS12 | |
| SCHEMBL6265376 | 0.71 | HPSE (0.82) | PRSS12RHEB | |
| SCHEMBL18229675 | 0.71 | HDAC6 (1.00) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL15717512 | 0.71 | PRSS12 (1.00) | PRSS12F2F10PLGPLAT | |
| SCHEMBL6483677 | 0.70 | PRSS12 (0.66) | PRSS12NR2E3CHEK2 | |
| SCHEMBL31748761 | 0.70 | PRSS12 (0.66) | PRSS12NR2E3CHEK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160274126-A1 | BIOMARKERS FOR THE DIAGNOSIS OF INTERSTITIAL CYSTITIS | WILLIAM BEAUMONT HOSPITAL | 2016-09-22 | — | — | US | disclosed |
| WO-2014078232-A1 | BIOMARKERS FOR THE DIAGNOSIS OF INTERSTITIAL CYSTITIS | WILLIAM BEAUMONT HOSPITAL (US) | 2014-05-22 | — | — | WO | disclosed |