Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 17/20 | 1.00 |
| ▸ | NFKB2 | Q00653 | 17/20 | 1.00 |
| ▸ | RELA | Q04206 | 17/20 | 1.00 |
| ▸ | NPC1 | O15118 | 1/20 | 1.00 |
| ▸ | POLB | P06746 | 1/20 | 1.00 |
| ▸ | MAPT | P10636 | 1/20 | 1.00 |
| ▸ | HTT | P42858 | 1/20 | 1.00 |
| ▸ | RAB9A | P51151 | 1/20 | 1.00 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 1.00 |
| ▸ | CLPX | O76031 | 1/20 | 0.81 |
| ▸ | VCP | P55072 | 1/20 | 0.81 |
| ▸ | RORA | P35398 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Withaferin A SCHEMBL12309163 | 1.00 | NFKB1 (1.00) | NFKB1NFKB2RELANPC1POLB | |
| Withaferin A SCHEMBL29398581 | 1.00 | NFKB1 (1.00) | NFKB1NFKB2RELANPC1POLB | |
| Withaferin A SCHEMBL30782710 | 1.00 | NFKB1 (1.00) | NFKB1NFKB2RELANPC1POLB | |
| Withaferin A SCHEMBL12309137 | 1.00 | NFKB1 (1.00) | NFKB1NFKB2RELANPC1POLB | |
| Withaferin A SCHEMBL20136632 | 1.00 | NFKB1 (1.00) | NFKB1NFKB2RELANPC1POLB | |
| Withaferin A SCHEMBL17807718 | 1.00 | NFKB1 (1.00) | NFKB1NFKB2RELANPC1POLB | |
| Withaferin A SCHEMBL24075907 | 1.00 | NFKB1 (1.00) | NFKB1NFKB2RELANPC1POLB | |
| Withaferin A SCHEMBL11950371 | 1.00 | NFKB1 (1.00) | NFKB1NFKB2RELANPC1POLB | |
| Withaferin A SCHEMBL18372363 | 1.00 | NFKB1 (1.00) | NFKB1NFKB2RELANPC1POLB | |
| SCHEMBL12309145 | 0.94 | NFKB1 (1.00) | NFKB1NFKB2RELANPC1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 4742 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260144836-A1 | NUTRACEUTICAL FOR ENHANCED COGNITIVE PERFORMANCE | Herbanized Wellness, LLC (US) | 2026-05-28 | — | — | US | claimed |
| US-20260144835-A1 | MULTIFUNCTIONAL NUTRACEUTICAL FOR ENHANCING FEMALE HEALTH | Beltran, Robert R. (US) | 2026-05-28 | — | — | US | claimed |
| EP-4746864-A1 | C5 KETONE COMPOSITIONS AND RELATED METHODS FOR TREATING METABOLIC DYSFUNCTION | Keto Innovations, LLC (US) | 2026-05-27 | — | — | EP | claimed |
| WO-2026107205-A1 | ANIMAL SUPPLEMENT FORMULATIONS AND METHODS THEREOF | ELANCO US INC. (US) | 2026-05-21 | — | — | WO | claimed |
| EP-4743437-A1 | DIESTER LIPIDS, LIPID NANOPARTICLE CONTAINING DIESTER LIPIDS, AND FORMULATIONS THEREOF | Providence Therapeutics Holdings Inc. (CA) | 2026-05-20 | — | — | EP | claimed |
| US-20260130924-A1 | COMPOSITIONS AND METHODS OF TREATING SUBJECTS WITH BRCA1 MUTATION OR DEFICIENCY | UNIV TEXAS (US) | 2026-05-14 | — | — | US | claimed |
| EP-4739299-A1 | MODELS OF CONE PHOTORECEPTOR DEGENERATION | SORBONNE UNIVERSITE (FR) | 2026-05-13 | — | — | EP | claimed |
| EP-4739328-A1 | COMPOSITION | Nicoventures Trading Limited (GB) | 2026-05-13 | — | — | EP | claimed |
| US-20260124218-A1 | Comprehensive Cannabinoid Compositions and Methods for the Management of Anxiety Disorders | PICAZO DANTE (US) | 2026-05-07 | — | — | US | claimed |
| EP-4735010-A1 | DENDRITIC CELLS LOADED WITH LYSATES FROM LATE FERROPTOTIC CELLS TO TREAT CANCER | Universiteit Gent (BE) | 2026-05-06 | — | — | EP | claimed |
| US-20050226950-A1 | Process for isolation of withaferin-A from plant materials and products therefrom | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2005-10-13 | — | — | US | claimed |
| EP-1569669-A2 | WITHANIA SOMNIFERA COMPOSITION, METHOD FOR OBTAINING SAME AND PHARMACEUTICAL, NUTRITIONAL AND PERSONAL CARE FORMULATIONS THEREOF | Natreon Inc. (US) | 2005-09-07 | — | — | EP | claimed |
| WO-2005077392-A1 | HERBAL FORMULATION COMPRISING EXTRACTS OF WITHANIA, TINOSPORA AND PICRORHIZA AS A PEDIATRIC TONIC | RANBAXY LABORATORIES LIMITED (IN) | 2005-08-25 | — | — | WO | claimed |
| EP-1562618-A1 | CYCLOOXYGENASE-2 INHIBITORY WITHANOLIDE COMPOSITIONS AND METHOD | Michigan State University (US) | 2005-08-17 | — | — | EP | claimed |
| US-20040258781-A1 | Cyclooxygenase-2 inhibitory withanolide compositions and method | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY | 2004-12-23 | — | — | US | claimed |
| US-20040166184-A1 | Withania somnifera composition, method for obtaining same and pharmaceutical, nutritional and personal care formulations thereof | NATREON INC. | 2004-08-26 | — | — | US | claimed |
| WO-2004050015-A2 | WITHANIA SOMNIFERA COMPOSITION, METHOD FOR OBTAINING SAME AND PHARMACEUTICAL, NUTRITIONAL AND PERSONAL CARE FORMULATIONS THEREOF | NATREON, INC. (US) | 2004-06-17 | — | — | WO | claimed |
| WO-2004043478-A1 | CYCLOOXYGENASE-2 INHIBITORY WITHANOLIDE COMPOSITIONS AND METHOD | MICHIGAN STATE UNIVERSITY (US) | 2004-05-27 | — | — | WO | claimed |
| US-20040096524-A1 | Cyclooxygenase-2 inhibitory withanolide compositions and method | MICHIGAN STATE UNIVERSITY (US) | 2004-05-20 | — | — | US | claimed |
| US-6153198-A | A PLANT ROOT EXTRACT, IN THE FORM OF A STABLE, DRY POWDER, PRODUCES A COGNITION EFFECT AND LEARNING ENHANCEMENT | NATREON INC. (US) | 2000-11-28 | — | — | US | claimed |